Evidence map›Paper›PMID 34200807›Full record

ArticleInternational journal of molecular sciences2021

Synthesis of Novel Acyl Derivatives of 3-(4,5,6,7-Tetrabromo-1

Konrad Chojnacki, Patrycja Wińska, Olena Karatsai, Mirosława Koronkiewicz, Małgorzata Milner-Krawczyk, Monika Wielechowska, Maria Jolanta Rędowicz, Maria Bretner, Paweł Borowiecki

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Identification of 4,5,6,7-Tetrabromo-1bioRxiv : the preprint server for biology · 2026
    Article
  2. Pro-Apoptotic Activity of 1-(4,5,6,7-Tetrabromo-1International journal of molecular sciences · 2025
    Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Konrad ChojnackiChair of Drug and Cosmetics Biotechnology, Faculty of Chemistry, Warsaw University of Technology, 00-664 Warsaw, Poland.
Patrycja WińskaChair of Drug and Cosmetics Biotechnology, Faculty of Chemistry, Warsaw University of Technology, 00-664 Warsaw, Poland.
Olena KaratsaiLaboratory of Molecular Basis of Cell Motility, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.ORCID 0000-0002-3753-5987
Mirosława KoronkiewiczDepartment of Drug Biotechnology and Bioinformatics, National Medicines Institute, 00-725 Warsaw, Poland.
Małgorzata Milner-KrawczykChair of Drug and Cosmetics Biotechnology, Faculty of Chemistry, Warsaw University of Technology, 00-664 Warsaw, Poland.ORCID 0000-0003-2032-0995
Monika WielechowskaChair of Drug and Cosmetics Biotechnology, Faculty of Chemistry, Warsaw University of Technology, 00-664 Warsaw, Poland.
Maria Jolanta RędowiczLaboratory of Molecular Basis of Cell Motility, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.ORCID 0000-0001-5834-471X
Maria BretnerChair of Drug and Cosmetics Biotechnology, Faculty of Chemistry, Warsaw University of Technology, 00-664 Warsaw, Poland.
Paweł BorowieckiChair of Drug and Cosmetics Biotechnology, Faculty of Chemistry, Warsaw University of Technology, 00-664 Warsaw, Poland.ORCID 0000-0001-5355-7281
Warsaw University of Technology · PLInstytut Biologii Doświadczalnej im. Marcelego Nenckiego · PLNarodowy Instytut Leków · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein kinase CK2 has been considered as an attractive drug target for anti-cancer therapy. The synthesis of

Indexed as

ApoptosisAntineoplastic AgentsBenzimidazolesBreast NeoplasmsCasein Kinase IICell ProliferationFemaleHumansMCF-7 CellsProtein Kinase InhibitorsStructure-Activity RelationshipAntineoplastic AgentsBenzimidazolesCasein Kinase IIProtein Kinase Inhibitorsapoptosisbreast cancerCK2 inhibitorsprodrug strategyprotein kinase CK2tetrabromobenzimidazole

Identifiers

PMID34200807
PMCPMC8230474
OpenAlexW3167246484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.