Evidence map›Paper›PMID 34200772›Full record

ArticleCells2021

A Distinct Faecal Microbiota and Metabolite Profile Linked to Bowel Habits in Patients with Irritable Bowel Syndrome.

Bani Ahluwalia, Cristina Iribarren, Maria K Magnusson, Johanna Sundin, Egbert Clevers, Otto Savolainen, Alastair B Ross, Hans Törnblom, Magnus Simrén, Lena Öhman

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Bani AhluwaliaDepartment of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0003-0299-7732
Cristina IribarrenDepartment of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0002-0632-7552
Maria K MagnussonDepartment of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, 405 30 Gothenburg, Sweden.
Johanna SundinDepartment of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, 405 30 Gothenburg, Sweden.
Egbert CleversDepartment of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, 413 45 Gothenburg, Sweden.
Otto SavolainenChalmers Mass Spectrometry Infrastructure, Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden.
Alastair B RossChalmers Mass Spectrometry Infrastructure, Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden.
Hans TörnblomDepartment of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, 413 45 Gothenburg, Sweden.
Magnus SimrénDepartment of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, 413 45 Gothenburg, Sweden.
Lena ÖhmanDepartment of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0001-8142-2106
University of Gothenburg · SEAgResearch · NZChalmers University of Technology · SEUniversity of North Carolina at Chapel Hill · US

Funding

AFA FörsäkringRegional Executive Board, Region Västra Götaland VGFOUREG-931919Sahlgrenska Academy, University of GothenburgSwedish Medical Research Council 13409Swedish Medical Research Council 2015-02317Swedish Medical Research Council 2019-01052Swedish Medical Research Council 21691Swedish Medical Research Council 21692
6 · The paper itself

Abstract

Patients with irritable bowel syndrome (IBS) are suggested to have an altered intestinal microenvironment. We therefore aimed to determine the intestinal microenvironment profile, based on faecal microbiota and metabolites, and the potential link to symptoms in IBS patients. The faecal microbiota was evaluated by the GA-map

Indexed as

AdultAgedCohort StudiesConstipationDiarrheaFecesFemaleGastrointestinal MicrobiomeHumansIrritable Bowel SyndromeMaleMiddle AgedRetrospective Studiesintestinal microenvironmentirritable bowel syndromemicrobial metabolitesmicrobiotapathophysiology

Identifiers

PMID34200772
PMCPMC8230381
OpenAlexW3171878901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.