Evidence map›Paper›PMID 34200716›Full record

ArticleMolecules (Basel, Switzerland)2021

Endosomal pH-Responsive Fe-Based Hyaluronate Nanoparticles for Doxorubicin Delivery.

Yangmun Bae, Yoonyoung Kim, Eun Seong Lee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yangmun BaeDepartment of Biotechnology, The Catholic University of Korea, 43 Jibong-ro, Bucheon-si 14662, Gyeonggi-do, Korea.
Yoonyoung KimDepartment of Biotechnology, The Catholic University of Korea, 43 Jibong-ro, Bucheon-si 14662, Gyeonggi-do, Korea.
Eun Seong LeeDepartment of Biotechnology, The Catholic University of Korea, 43 Jibong-ro, Bucheon-si 14662, Gyeonggi-do, Korea.ORCID 0000-0002-4087-2407
Catholic University of Korea · KR

Funding

the Catholic University of Korea the Research Fund, 2021the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) NRF-2021R1A2B5B01001932
6 · The paper itself

Abstract

In this study, we report pH-responsive metal-based biopolymer nanoparticles (NPs) for tumor-specific chemotherapy. Here, aminated hyaluronic acid (aHA) coupled with 2,3-dimethylmaleic anhydride (DMA, as a pH-responsive moiety) (aHA-DMA) was electrostatically complexed with ferrous chloride tetrahydrate (FeCl

Indexed as

AnimalsAntineoplastic AgentsCell Line, TumorDoxorubicinDrug CarriersDrug Delivery SystemsEndocytosisEndosomesFemaleFerrous CompoundsHumansHyaluronan ReceptorsHyaluronic AcidHydrogen-Ion ConcentrationMiceMice, Inbred BALB CAntineoplastic AgentsDoxorubicinDrug Carriersferrous chlorideFerrous CompoundsHyaluronan ReceptorsHyaluronic AcidCD44 receptor-mediated endocytosisendosomal pH-responsive hyaluronateFe-based nanoparticlestumor therapy

Identifiers

PMID34200716
PMCPMC8229704
OpenAlexW3168542247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.