Evidence map›Paper›PMID 34200699›Full record

Trial reportBiomolecules2021

Survival of Laryngeal Cancer Patients Depending on Zinc Serum Level and Oxidative Stress Genotypes.

Jakub Lubiński, Ewa Jaworowska, Róża Derkacz, Wojciech Marciniak, Katarzyna Białkowska, Piotr Baszuk, Rodney J Scott, Jan A Lubiński

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Investigation of imbalances in essential/toxic metal levels in the blood of laryngeal cancer patients in comparison with controls.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023
    Article
  13. Article
  14. Gene polymorphisms and prognosis of head and neck squamous cell carcinoma: a systematic review.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Jakub LubińskiClinic of Otolaryngology, Pomeranian Medical University, Unii Lubelskiej 1, 71-252 Szczecin, Poland.
Ewa JaworowskaClinic of Otolaryngology, Pomeranian Medical University, Unii Lubelskiej 1, 71-252 Szczecin, Poland.
Róża DerkaczReadGene, Alabastrowa 8, 72-003 Grzepnica, Poland.
Wojciech MarciniakReadGene, Alabastrowa 8, 72-003 Grzepnica, Poland.
Katarzyna BiałkowskaDepartment of Genetics and Pathology, International Hereditary Cancer Centre, Pomeranian Medical University, Unii Lubelskiej 1, 71-252 Szczecin, Poland.
Piotr BaszukDepartment of Genetics and Pathology, International Hereditary Cancer Centre, Pomeranian Medical University, Unii Lubelskiej 1, 71-252 Szczecin, Poland.ORCID 0000-0002-0676-2597
Rodney J ScottDiscipline of Medical Genetics, Faculty of Health, School of Biomedical Sciences, University of Newcastle, Callaghan, NSW 2308, Australia.ORCID 0000-0001-7724-3404
Jan A LubińskiReadGene, Alabastrowa 8, 72-003 Grzepnica, Poland.ORCID 0000-0003-2931-3003
International Hereditary Cancer Center · PLRead-Gene (Poland) · PLHunter Medical Research Institute · AUPomeranian Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stress contributes to various aspects of malignancy and could influence survival in laryngeal cancer patients. Among antioxidant mechanisms, zinc and the antioxidant enzymes superoxide dismutase 2, catalase and glutathione peroxidase 1 play a major role. The aim of this study was a prospective evaluation of the survival of patients with laryngeal cancer in relation to serum levels of zinc in combination with functional genotype differences of three key antioxidant enzymes. The study group consisted of 300 patients treated surgically for laryngeal cancer. Serum zinc levels and common polymorphisms in

Indexed as

GenotypeLaryngeal NeoplasmsOxidative StressAdultAgedAged, 80 and overDisease-Free SurvivalFemaleHumansMaleMiddle AgedNeoplasm ProteinsSurvival RateZincNeoplasm ProteinsZincantioxidant enzymeslaryngeal cancerzinc

Identifiers

PMID34200699
PMCPMC8228711
OpenAlexW3170735510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.