Evidence map›Paper›PMID 34200688›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Antiprotozoal

Lara U Szabó, Marcel Kaiser, Pascal Mäser, Thomas J Schmidt

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Antiprotozoal Aminosteroid Alkaloids fromMolecules (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. International journal of molecular sciences · 2025
    Article
  7. Antiprotozoal Aminosteroids fromMolecules (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Hydroalcoholic extract ofFrontiers in pharmacology · 2023
    Article
  12. Plant Terpenoids as Hit Compounds against Trypanosomiasis.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  13. Investigation of the Variability of Alkaloids inMolecules (Basel, Switzerland) · 2021
    Article
  14. Identification of Antiprotozoal Compounds fromMolecules (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lara U SzabóInstitute of Pharmaceutical Biology and Phytochemistry (IPBP), University of Münster, PharmaCampus Corrensstraße 48, D-48149 Münster, Germany.ORCID 0000-0001-8654-5965
Marcel KaiserSwiss Tropical and Public Health Institute (Swiss TPH), Socinstrasse 57, CH-4051 Basel, Switzerland.
Pascal MäserSwiss Tropical and Public Health Institute (Swiss TPH), Socinstrasse 57, CH-4051 Basel, Switzerland.ORCID 0000-0003-3122-1941
Thomas J SchmidtInstitute of Pharmaceutical Biology and Phytochemistry (IPBP), University of Münster, PharmaCampus Corrensstraße 48, D-48149 Münster, Germany.ORCID 0000-0003-2634-9705

Funding

Apothekerstiftung Westfalen-Lippe Doctoral fellowship, no grant number
6 · The paper itself

Abstract

Malaria and human African trypanosomiasis (HAT; sleeping sickness) are life-threatening tropical diseases caused by protozoan parasites. Due to limited therapeutic options, there is a compelling need for new antiprotozoal agents. In a previous study, O-tigloylcyclovirobuxeine-B was recovered from a

Indexed as

antiprotozoal activityBuxus sempervirens L.natural product isolationnor-cycloartane alkaloidsstructure elucidation

Identifiers

PMID34200688
PMCPMC8228141

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.