Evidence map›Paper›PMID 34200662›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Super-Cationic Peptide Dendrimers-Synthesis and Evaluation as Antimicrobial Agents.

Estelle J Ramchuran, Isabel Pérez-Guillén, Linda A Bester, René Khan, Fernando Albericio, Miguel Viñas, Beatriz G de la Torre

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Estelle J RamchuranBiomedical Resource Unit, School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban 4000, South Africa.ORCID 0000-0003-1829-8880
Isabel Pérez-GuillénLab Molecular Microbiology & Antimicrobials, Department of Pathology and Experimental Therapeutics, Medical School-IDIBELL, University of Barcelona, Hospitalet, 08907 Barcelona, Spain.
Linda A BesterBiomedical Resource Unit, School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban 4000, South Africa.ORCID 0000-0001-5726-681X
René KhanDiscipline of Medical Biochemistry, School of Laboratory Medicine and Medical Science, University of KwaZulu-Natal, Durban 4001, South Africa.ORCID 0000-0002-3589-6869
Fernando AlbericioPeptide Sciences Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, University Road, Westville, Durban 4001, South Africa.ORCID 0000-0002-8946-0462
Miguel ViñasLab Molecular Microbiology & Antimicrobials, Department of Pathology and Experimental Therapeutics, Medical School-IDIBELL, University of Barcelona, Hospitalet, 08907 Barcelona, Spain.ORCID 0000-0003-2073-3386
Beatriz G de la TorreKRISP, College of Health Sciences, University of KwaZulu-Natal, Westville, Durban 4001, South Africa.ORCID 0000-0001-8521-9172

Funding

Fundació la Marató de TV3 #20183530
6 · The paper itself

Abstract

Microbial infections are a major public health concern. Antimicrobial peptides (AMPs) have been demonstrated to be a plausible alternative to the current arsenal of drugs that has become inefficient due to multidrug resistance. Herein we describe a new AMP family, namely the super-cationic peptide dendrimers (SCPDs). Although all members of the series exert some antibacterial activity, we propose that special attention should be given to (KLK)

Indexed as

antimicrobial peptidesGram-negativeGram-positivesolid-phase peptide synthesistherapeutic index

Identifiers

PMID34200662
PMCPMC8228121

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.