Evidence map›Paper›PMID 34200577›Full record

ArticleMetabolites2021

Circulating Levels of Pro-Neurotensin and Its Relationship with Nonalcoholic Steatohepatitis and Hepatic Lipid Metabolism.

Beatriz Villar, Laia Bertran, Carmen Aguilar, Jessica Binetti, Salomé Martínez, Fàtima Sabench, Monica Real, David Riesco, Marta París, Daniel Del Castillo and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06453239 (Assessment the Diagnostic Value of Pro-Neurotensin as a Serum Biomarker in Metabolic Dysfunction-associated Steatotic Liver Disease), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06453239 unknown statusnot on this mapstarted 2024, after this paper: background citation

Assessment the Diagnostic Value of Pro-Neurotensin as a Serum Biomarker in Metabolic Dysfunction-associated Steatotic Liver Disease

TypeobservationalSponsorSohag UniversityRan2024 to 2025Enrolled80ConditionsSteatosis of LiverArmsPro-Neurotensin level as a Serum Biomarker
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. New Insights in the Control of Fat Homeostasis: The Role of Neurotensin.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Beatriz VillarServei Medicina Interna, Hospital Universitari Joan XXIII, Universitat Rovira i Virgili, 4, 43007 Tarragona, Spain.
Laia BertranGrup d'Estudi de Malalties Metabòliques associades a Insulino Resistència (GEMMAIR)-AGAUR, Departament de Medicina i Cirurgia, Institut d'Investigació Sanitària Pere Virgili (IISPV), Universitat Rovira i Virgili, 4, 43007 Tarragona, Spain.ORCID 0000-0001-9052-1368
Carmen AguilarGrup d'Estudi de Malalties Metabòliques associades a Insulino Resistència (GEMMAIR)-AGAUR, Departament de Medicina i Cirurgia, Institut d'Investigació Sanitària Pere Virgili (IISPV), Universitat Rovira i Virgili, 4, 43007 Tarragona, Spain.
Jessica BinettiServei Medicina Interna, Hospital Universitari Joan XXIII, Universitat Rovira i Virgili, 4, 43007 Tarragona, Spain.
Salomé MartínezServei Anatomia Patològica, Hospital Universitari Joan XXIII Tarragona, 4, 43007 Tarragona, Spain.
Fàtima SabenchServei de Cirurgia, Hospital Sant Joan de Reus, Institut d'Investigació Sanitària Pere Virgili. Avinguda, Departament de Medicina i Cirurgia, Universitat Rovira i Virgili, 2, 43204 Reus, Spain.
Monica RealServei Medicina Interna, Hospital Universitari Joan XXIII, Universitat Rovira i Virgili, 4, 43007 Tarragona, Spain.
David RiescoServei Medicina Interna, Hospital Universitari Joan XXIII, Universitat Rovira i Virgili, 4, 43007 Tarragona, Spain.
Marta ParísServei de Cirurgia, Hospital Sant Joan de Reus, Institut d'Investigació Sanitària Pere Virgili. Avinguda, Departament de Medicina i Cirurgia, Universitat Rovira i Virgili, 2, 43204 Reus, Spain.
Daniel Del CastilloServei de Cirurgia, Hospital Sant Joan de Reus, Institut d'Investigació Sanitària Pere Virgili. Avinguda, Departament de Medicina i Cirurgia, Universitat Rovira i Virgili, 2, 43204 Reus, Spain.
Cristóbal RichartGrup d'Estudi de Malalties Metabòliques associades a Insulino Resistència (GEMMAIR)-AGAUR, Departament de Medicina i Cirurgia, Institut d'Investigació Sanitària Pere Virgili (IISPV), Universitat Rovira i Virgili, 4, 43007 Tarragona, Spain.
Teresa AuguetServei Medicina Interna, Hospital Universitari Joan XXIII, Universitat Rovira i Virgili, 4, 43007 Tarragona, Spain.ORCID 0000-0003-0396-6428
Institut de Recerca Biomèdica Catalunya Sud · ESHospital Universitari Joan XXIII de Tarragona · ES

Funding

Instituto de Salud Carlos III PI16/00498
6 · The paper itself

Abstract

Recent studies suggest a link between pro-neurotensin (pro-NT) and nonalcoholic fatty liver disease (NAFLD), but the published data are conflicting. Thus, we aimed to analyze pro-NT levels in women with morbid obesity (MO) and NAFLD to investigate if this molecule is involved in NAFLD and liver lipid metabolism. Plasma levels of pro-NT were determined in 56 subjects with MO and 18 with normal weight (NW). All patients with MO were subclassified according to their liver histology into the normal liver (NL,

Indexed as

lipid metabolismneurotensinnonalcoholic fatty liver diseasenonalcoholic steatohepatitispro-neurotensin

Identifiers

PMID34200577
PMCPMC8226510
OpenAlexW3172047098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.