Evidence map›Paper›PMID 34200530›Full record

ArticleSensors (Basel, Switzerland)2021

Measuring Gait Stability in People with Multiple Sclerosis Using Different Sensor Locations and Time Scales.

Roy Müller, Lucas Schreff, Lisa-Eyleen Koch, Patrick Oschmann, Daniel Hamacher

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Roy MüllerDepartment of Orthopedic Surgery, Klinikum Bayreuth GmbH, 95445 Bayreuth, Germany.ORCID 0000-0002-4688-1515
Lucas SchreffDepartment of Orthopedic Surgery, Klinikum Bayreuth GmbH, 95445 Bayreuth, Germany.
Lisa-Eyleen KochDepartment of Orthopedic Surgery, Klinikum Bayreuth GmbH, 95445 Bayreuth, Germany.
Patrick OschmannDepartment of Neurology, Klinikum Bayreuth GmbH, 95445 Bayreuth, Germany.
Daniel HamacherDepartment of Sports Science, Friedrich Schiller University Jena, 07749 Jena, Germany.ORCID 0000-0002-2296-4316
Bayreuth Medical Center · DEFriedrich Schiller University Jena · DE

Funding

Sanofi Genzyme GZ-2017-11742
6 · The paper itself

Abstract

The evaluation of local divergence exponent (LDE) has been proposed as a common gait stability measure in people with multiple sclerosis (PwMS). However, differences in methods of determining LDE may lead to different results. Therefore, the purpose of the current study was to determine the effect of different sensor locations and LDE measures on the sensitivity to discriminate PwMS. To accomplish this, 86 PwMS and 30 healthy participants were instructed to complete a six-minute walk wearing inertial sensors attached to the foot, trunk and lumbar spine. Due to possible fatigue effects, the LDE short (~50% of stride) and very short (~5% of stride) were calculated for the remaining first, middle and last 30 strides. The effect of group (PwMS vs. healthy participants) and time (begin, mid, end) and the effect of Expanded Disability Status Scale (EDSS) and time were assessed with linear random intercepts models. We found that perturbations seem to be better compensated in healthy participants on a longer time scale based on trunk movements and on a shorter time scale (almost instantaneously) according to the foot kinematics. Therefore, we suggest to consider both sensor location and time scale of LDE when calculating local gait stability in PwMS.

Indexed as

Multiple SclerosisBiomechanical PhenomenaFatigueGaitHumansWalking25-foot walk6-min walkEDSSfatiguelocal dynamic stabilityLyapunov exponentMS

Identifiers

PMID34200530
PMCPMC8228118
OpenAlexW3170459435

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.