Evidence map›Paper›PMID 34200519›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Elucidating the Antimycobacterial Mechanism of Action of Decoquinate Derivative RMB041 Using Metabolomics.

Kirsten E Knoll, Zander Lindeque, Adetomiwa A Adeniji, Carel B Oosthuizen, Namrita Lall, Du Toit Loots

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. The metabolomics of a protein kinase C delta (PKCδ) knock-out mouse model.Metabolomics : Official journal of the Metabolomic Society · 2022
    Article
  6. Review
  7. Microbiology spectrum · 2022
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Kirsten E KnollHuman Metabolomics, North-West University, Private Bag x6001, Box 269, Potchefstroom 2531, South Africa.
Zander LindequeHuman Metabolomics, North-West University, Private Bag x6001, Box 269, Potchefstroom 2531, South Africa.ORCID 0000-0001-8017-4278
Adetomiwa A AdenijiHuman Metabolomics, North-West University, Private Bag x6001, Box 269, Potchefstroom 2531, South Africa.
Carel B OosthuizenDepartment of Plant and Soil Sciences, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria 0002, South Africa.ORCID 0000-0003-0940-8099
Namrita LallDepartment of Plant and Soil Sciences, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria 0002, South Africa.ORCID 0000-0002-3242-3476
Du Toit LootsHuman Metabolomics, North-West University, Private Bag x6001, Box 269, Potchefstroom 2531, South Africa.ORCID 0000-0002-0339-6237
North-West University · ZAUniversity of Pretoria · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB), caused by

Indexed as

decoquinate derivative RMB041GCxGC-TOFMSmechanism of actionmetabolomicsMycobacterium tuberculosistuberculosis

Identifiers

PMID34200519
PMCPMC8228794
OpenAlexW3171664832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.