Evidence map›Paper›PMID 34200366›Full record

SynthesisNutrients2021

Magnesium Metabolism in Chronic Alcohol-Use Disorder: Meta-Analysis and Systematic Review.

Flora O Vanoni, Gregorio P Milani, Carlo Agostoni, Giorgio Treglia, Pietro B Faré, Pietro Camozzi, Sebastiano A G Lava, Mario G Bianchetti, Simone Janett

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Impact of adolescents' binge drinking on blood chemistry.European journal of pediatrics · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Flora O VanoniFamily Medicine Institute, Faculty of Biomedical Science, Università della Svizzera Italiana, 6900 Lugano, Switzerland.
Gregorio P MilaniPediatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0003-3829-4254
Carlo AgostoniPediatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0002-5006-0832
Giorgio TregliaAcademic Education, Research and Innovation Area, General Directorate, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.ORCID 0000-0001-9808-780X
Pietro B FaréDepartment of Internal Medicine, Ente Ospedaliero Cantonale, 6600 Locarno, Switzerland.ORCID 0000-0003-0944-2609
Pietro CamozziDepartment of Internal Medicine, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.
Sebastiano A G LavaPediatric Cardiology Unit, Department of Pediatrics, Centre Hospitalier Universitaire Vaudois, University of Lausanne, 1011 Lausanne, Switzerland.
Mario G BianchettiFamily Medicine Institute, Faculty of Biomedical Science, Università della Svizzera Italiana, 6900 Lugano, Switzerland.
Simone JanettDepartment of Internal Medicine, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.
Ente Ospedaliero Cantonale · CHUniversità della Svizzera italiana · CHUniversity of Milan · ITUniversity Hospital of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic alcohol-use disorder has been imputed as a possible cause of dietary magnesium depletion. The purpose of this study was to assess the prevalence of hypomagnesemia in chronic alcohol-use disorder, and to provide information on intracellular magnesium and on its renal handling. We carried out a structured literature search up to November 2020, which returned 2719 potentially relevant records. After excluding non-significant records, 25 were retained for the final analysis. The meta-analysis disclosed that both total and ionized circulating magnesium are markedly reduced in chronic alcohol-use disorder. The funnel plot and the Egger's test did not disclose significant publication bias. The I

Indexed as

AlcoholismChronic DiseaseExtracellular SpaceHumansIntracellular SpaceIonsMagnesiumOrgan SpecificityPublication BiasIonsMagnesiumalcohol-usedepletiondietelectrolyteshypomagnesemiakidneymagnesium

Identifiers

PMID34200366
PMCPMC8229336
OpenAlexW3169301537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.