Evidence map›Paper›PMID 34200339›Full record

ReviewJournal of clinical medicine2021

Physical Activity in Patients with Prader-Willi Syndrome-A Systematic Review of Observational and Interventional Studies.

Alice Bellicha, Muriel Coupaye, Héléna Mosbah, Maithé Tauber, Jean-Michel Oppert, Christine Poitou

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Current Treatments for Patients with Genetic ObesityJournal of clinical research in pediatric endocrinology · 2023
    Review
  5. Article
  6. Review
  7. Review
  8. Observational
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Alice BellichaINSERM, Nutrition and Obesities: Systemic Approaches (NutriOmics), Research Unit, Sorbonne University, F-75013 Paris, France.ORCID 0000-0002-5572-487X
Muriel CoupayeAssistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêrière Hospital, Department of Nutrition, Rare Diseases Center of Reference 'Prader-Willi Syndrome and Obesity with Eating Disorders' (PRADORT), Sorbonne University, F-75013 Paris, France.
Héléna MosbahAssistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêrière Hospital, Department of Nutrition, Rare Diseases Center of Reference 'Prader-Willi Syndrome and Obesity with Eating Disorders' (PRADORT), Sorbonne University, F-75013 Paris, France.ORCID 0000-0001-7360-4209
Maithé TauberCentre de Référence du Syndrome de Prader-Willi, Hôpital des Enfants, Axe Pédiatrique du CIC 9302/INSERM, Hôpital des Enfants, Institut Toulousain des Maladies Infectieuses et Inflammatoires, INSERM UMR1291, CNRS UMR5051, Université Toulouse III, F-31000 Toulouse, France.
Jean-Michel OppertAssistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêrière Hospital, Department of Nutrition, Rare Diseases Center of Reference 'Prader-Willi Syndrome and Obesity with Eating Disorders' (PRADORT), Sorbonne University, F-75013 Paris, France.
Christine PoitouINSERM, Nutrition and Obesities: Systemic Approaches (NutriOmics), Research Unit, Sorbonne University, F-75013 Paris, France.
Sorbonne Université · FRInserm · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity (PA) is an important aspect of the management of patients with Prader-Willi syndrome (PWS). However, the day-to-day implementation of PA programs is particularly challenging in these patients. This systematic review aimed (1) to describe habitual PA and sedentary behavior and (2) to assess the effects of PA interventions and to describe their implementation process, in children and adults with PWS. A systematic search of controlled trials, single-group interventions, observational, and qualitative studies published up to December 2020 was performed. Twenty-five studies were included. Habitual PA was found to be lower in patients with PWS compared to controls without obesity or with non-syndromic obesity. Habitual PA was positively associated with lean body mass and bone parameters in children with PWS, and these finding were strengthened by intervention studies reporting an increase in both outcomes after a PA program. PA programs also improved physical function (muscle strength, walking distance, and coordination), without significant effect on weight and fat mass. Attendance to exercise sessions was usually high and no serious adverse effect was reported. In conclusion, supervised PA programs are beneficial for children and adults with PWS. Support should be provided to families to facilitate their implementation in real-life settings.

Indexed as

implementationphysical activityPrader-Willi syndromesedentary timesyndromic obesitiessystematic review

Identifiers

PMID34200339
PMCPMC8201387
OpenAlexW3170990163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.