Evidence map›Paper›PMID 34200261›Full record

ArticleGenes2021

High SGO2 Expression Predicts Poor Overall Survival: A Potential Therapeutic Target for Hepatocellular Carcinoma.

Min Deng, Shaohua Li, Jie Mei, Wenping Lin, Jingwen Zou, Wei Wei, Rongping Guo

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Min DengDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.ORCID 0000-0002-6775-2210
Shaohua LiDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Jie MeiDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Wenping LinDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Jingwen ZouDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Wei WeiDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Rongping GuoDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.ORCID 0000-0003-2799-3463
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shugoshin2 (SGO2) may participate in the occurrence and development of tumors by regulating abnormal cell cycle division, but its prognostic value in hepatocellular carcinoma (HCC) remains unclear. In this study, we accessed The Cancer Genome Atlas (TCGA) database to get the clinical data and gene expression profile of HCC. The expression of SGO2 in HCC tissues and nontumor tissues and the relationship between SGO2 expression, survival, and clinicopathological parameters were analyzed. The SGO2 expression level was significantly higher in HCC tissues than in nontumor tissues (

Indexed as

Biomarkers, TumorCarcinoma, HepatocellularCell Cycle ProteinsFemaleHumansLiver NeoplasmsMaleMiddle AgedSurvival AnalysisUp-RegulationBiomarkers, TumorCell Cycle ProteinsSGO2 protein, humanbioinformaticshepatocellular carcinomaoutcomeSGO2survivaltherapeutic target

Identifiers

PMID34200261
PMCPMC8226836
OpenAlexW3166965486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.