Evidence map›Paper›PMID 34200245›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Feasibility of

Rossella Bruno, Elisa Sensi, Cristiana Lupi, Mirella Giordano, Laura Bernardini, Caterina Vivaldi, Lorenzo Fornaro, Enrico Vasile, Daniela Campani, Gabriella Fontanini

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Rossella BrunoUnit of Pathological Anatomy, University Hospital of Pisa, 56126 Pisa, Italy.
Elisa SensiUnit of Pathological Anatomy, University Hospital of Pisa, 56126 Pisa, Italy.
Cristiana LupiUnit of Pathological Anatomy, University Hospital of Pisa, 56126 Pisa, Italy.
Mirella GiordanoDepartment of Translational Research and of New Surgical and Medical Technologies, University of Pisa, 56126 Pisa, Italy.
Laura BernardiniDepartment of Translational Research and of New Surgical and Medical Technologies, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0003-1628-5170
Caterina VivaldiDepartment of Translational Research and of New Surgical and Medical Technologies, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0001-9307-2326
Lorenzo FornaroUnit of Medical Oncology, University Hospital of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-0187-5904
Enrico VasileUnit of Medical Oncology, University Hospital of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-8482-6963
Daniela CampaniDepartment of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0001-5987-734X
Gabriella FontaniniDepartment of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, 56126 Pisa, Italy.
Azienda Ospedaliera Universitaria Pisana · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer, with most patients diagnosed at advanced stages. First-line treatment based on a combined chemotherapy (FOLFIRINOX or gemcitabine plus nab-paclitaxel) provides limited benefits. Olaparib, a PARP inhibitor, has been approved as maintenance for PDAC patients harboring germline

Indexed as

BRCA1/2next generation sequencingpancreatic cancerPARP inhibitors

Identifiers

PMID34200245
PMCPMC8227758
OpenAlexW3172946220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.