Evidence map›Paper›PMID 34200196›Full record

ReviewMolecules (Basel, Switzerland)2021

Bisindole Alkaloids from the

Kamal P Pandey, Md Toufiqur Rahman, James M Cook

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  6. FeClRSC advances · 2025
    Article
  7. Review
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  11. Review
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  13. Article
  14. Alkaloids in Future Drug Discovery.Molecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kamal P PandeyDepartment of Chemistry and Biochemistry, University of Wisconsin Milwaukee, Milwaukee, WI 53211, USA.
Md Toufiqur RahmanRTI International, Center for Drug Discovery, Research Triangle Park, Durham, NC 27709, USA.ORCID 0000-0003-2752-6822
James M CookDepartment of Chemistry and Biochemistry, University of Wisconsin Milwaukee, Milwaukee, WI 53211, USA.ORCID 0000-0001-5512-3022
University of Wisconsin–Milwaukee · USRTI International · US

Funding

A Parent Intervention to Prevent Latino Youth Drug UseR21DA014617 · NIDA · OREGON SOCIAL LEARNING CENTER, INC. · PI MARTINEZ, CHARLES R · 2001 to 2004
$615k
NIDA NIH HHS R21-AA14617
6 · The paper itself

Abstract

Bisindoles are structurally complex dimers and are intriguing targets for partial and total synthesis. They exhibit stronger biological activity than their corresponding monomeric units. Alkaloids, including those containing C-19 methyl-substitution in their monomeric units, their synthetic derivatives, and their mismatched pairs can be attractive targets for synthesis and may unlock better drug targets. We herein discuss the isolation of bisindoles from various

Indexed as

AlkaloidsAlstoniaHumansIndole AlkaloidsOxindolesPharmaceutical PreparationsSpiro CompoundsAlkaloidsalstonisinedispegatrineIndole AlkaloidsmacralstonineOxindolesPharmaceutical PreparationsSpiro CompoundsvillalstonineajmalineAlstoniaApocynaceaebioactivitybiomimetic or total synthesisbiosynthesisbisindole synthesismacrolinepartialpleiocarpaminesarpagine

Identifiers

PMID34200196
PMCPMC8201064
OpenAlexW3168324724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.