Evidence map›Paper›PMID 34200194›Full record

ReviewChildren (Basel, Switzerland)2021

Novel Treatments and Technologies Applied to the Cure of Neuroblastoma.

Irene Paraboschi, Laura Privitera, Gabriela Kramer-Marek, John Anderson, Stefano Giuliani

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
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  11. Article
  12. Article
  13. Article
  14. Review
  15. Surgical Advances in Paediatric Neuroblastoma.Children (Basel, Switzerland) · 2022
    Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Irene ParaboschiWellcome/EPSRC Centre for Interventional & Surgical Sciences, University College London, London WC1E 6BT, UK.ORCID 0000-0003-3529-1437
Laura PriviteraWellcome/EPSRC Centre for Interventional & Surgical Sciences, University College London, London WC1E 6BT, UK.
Gabriela Kramer-MarekPreclinical Molecular Imaging, Division of Radiotherapy and Imaging, The Institute of Cancer Research, London SM2 5NG, UK.ORCID 0000-0002-8053-3880
John AndersonCancer Section, Developmental Biology and Cancer Programme, UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.ORCID 0000-0001-7509-3203
Stefano GiulianiWellcome/EPSRC Centre for Interventional & Surgical Sciences, University College London, London WC1E 6BT, UK.ORCID 0000-0002-4555-3093

Funding

Medical Research Council MR/T005491/1Wellcome Trust
6 · The paper itself

Abstract

Neuroblastoma (NB) is the most common extracranial solid tumour in childhood, accounting for approximately 15% of all cancer-related deaths in the paediatric population1. It is characterised by heterogeneous clinical behaviour in neonates and often adverse outcomes in toddlers. The overall survival of children with high-risk disease is around 40-50% despite the aggressive treatment protocols consisting of intensive chemotherapy, surgery, radiation therapy and hematopoietic stem cell transplantation2,3. There is an ongoing research effort to increase NB's cellular and molecular biology knowledge to translate essential findings into novel treatment strategies. This review aims to address new therapeutic modalities emerging from preclinical studies offering a unique translational opportunity for NB treatment.

Indexed as

Antibody-Drug Conjugates-Based Therapycellular immunotherapiesDrug-Loaded Nanoparticlesintra-operative treatmentsMonoclonal AntibodiesNeuroblastomaradiation therapiesThird-Generation Tyrosine Kinase Inhibitortumour vaccines

Identifiers

PMID34200194
PMCPMC8226870

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.