Evidence map›Paper›PMID 34200159›Full record

ArticleInfectious disease reports2021

Potential Misdiagnosis between COVID-19 and Dengue Infection Using Rapid Serological Test.

Siti Qamariyah Khairunisa, Ilham Harlan Amarullah, Siti Churrotin, Anisa Lailatul Fitria, Mochammad Amin, Maria Inge Lusida, Soegeng Soegijanto

Open access · goldAbstract read
In one paragraph

Article in Infectious disease reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Performance of VIDASDiagnostics (Basel, Switzerland) · 2023
    Article
  11. Dengue amid COVID-19 pandemic.PLOS global public health · 2023
    Article
  12. Article
  13. Capacitive immunosensor for COVID-19 diagnosis.Microelectronic engineering · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Coinfection and cross-reaction of dengue and COVID-19: a case series analysis.Revista da Sociedade Brasileira de Medicina Tropical · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Siti Qamariyah KhairunisaInstitute of Tropical Disease, Universitas Airlangga, Surabaya 60115, Indonesia.
Ilham Harlan AmarullahInstitute of Tropical Disease, Universitas Airlangga, Surabaya 60115, Indonesia.
Siti ChurrotinInstitute of Tropical Disease, Universitas Airlangga, Surabaya 60115, Indonesia.
Anisa Lailatul FitriaInstitute of Tropical Disease, Universitas Airlangga, Surabaya 60115, Indonesia.ORCID 0000-0002-9620-4002
Mochammad AminInstitute of Tropical Disease, Universitas Airlangga, Surabaya 60115, Indonesia.
Maria Inge LusidaInstitute of Tropical Disease, Universitas Airlangga, Surabaya 60115, Indonesia.
Soegeng SoegijantoInstitute of Tropical Disease, Universitas Airlangga, Surabaya 60115, Indonesia.
Airlangga University · ID

Funding

Universitas Airlangga 1093/UN3.14/PT/2020
6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) pandemic that has a significant rapid transmission is an international public health concern. Several dengue-endemic countries reported similar clinical and laboratory features between COVID-19 and dengue in the early incubation period, and thus discerning the infection is difficult. As a dengue-endemic country, Indonesia also poses the same challenge during the COVID-19 outbreak. This current study analyzed the IgG and IgM profiles from COVID-19 patients by using a serological SARS-CoV-2 and dengue rapid test. In addition, 38 sera from healthy individuals (pre-COVID-19 date) were analyzed using a dengue rapid test. Among 120 samples, 4 samples indicated dengue IgG positive. However, IgM, NS1, and RT-PCR analyses showed negative results. Interestingly, regarding seropositivity of NS1 and DENV IgG from healthy individuals (pre COVID-19 infection), two samples were positive DENV IgG, while one of them was positive NS1. This suggested that in the dengue-endemic area, many people have already experienced dengue and have immunity against dengue virus. There is also the possibility of antibody cross-reactivity between COVID-19 and dengue infection. This also emphasizes the high demand for a rapid method with high sensitivity and specificity that can distinguish between SARS-CoV-2 and dengue.

Indexed as

COVID-19cross-reactivitydenguerapid serological testSars-Cov 2

Identifiers

PMID34200159
PMCPMC8293083
OpenAlexW3166332141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.