Evidence map›Paper›PMID 34200147›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Genotoxicity and Gene Expression in the Rat Lung Tissue following Instillation and Inhalation of Different Variants of Amorphous Silica Nanomaterials (aSiO

Fátima Brandão, Carla Costa, Maria João Bessa, Elise Dumortier, Florence Debacq-Chainiaux, Roland Hubaux, Michel Salmon, Julie Laloy, Miruna S Stan, Anca Hermenean and 7 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Phytochemical Composition and Protective Effect ofMolecules (Basel, Switzerland) · 2022
    Article
  4. Article
  5. Cytotoxicity and Genotoxicity of Nanomaterials.Nanomaterials (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 5 countries.

Fátima BrandãoEPIUnit-Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas, 4050-600 Porto, Portugal.ORCID 0000-0002-2933-8561
Carla CostaEPIUnit-Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas, 4050-600 Porto, Portugal.ORCID 0000-0002-0027-8462
Maria João BessaEPIUnit-Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas, 4050-600 Porto, Portugal.
Elise DumortierUnité de Recherche en Biologie Cellulaire (URBC), Namur Research Institute for Life Sciences (Narilis), University of Namur, 5000 Namur, Belgium.
Florence Debacq-ChainiauxUnité de Recherche en Biologie Cellulaire (URBC), Namur Research Institute for Life Sciences (Narilis), University of Namur, 5000 Namur, Belgium.
Roland HubauxStratiCELL Laboratories, Research and Development, 5032 Les Isnes, Belgium.ORCID 0000-0002-3251-4028
Michel SalmonStratiCELL Laboratories, Research and Development, 5032 Les Isnes, Belgium.
Julie LaloyNamur Nanosafety Centre, Department of Pharmacy, Namur Research Institute for Life Sciences (Narilis), University of Namur, 5000 Namur, Belgium.ORCID 0000-0001-9570-6070
Miruna S StanDepartment of Biochemistry and Molecular Biology, University of Bucharest, 050095 Bucharest, Romania.ORCID 0000-0002-6273-8540
Anca HermeneanDepartment of Biochemistry and Molecular Biology, University of Bucharest, 050095 Bucharest, Romania.ORCID 0000-0001-8510-6653
Sami GharbiaDepartment of Biochemistry and Molecular Biology, University of Bucharest, 050095 Bucharest, Romania.
Anca DinischiotuDepartment of Biochemistry and Molecular Biology, University of Bucharest, 050095 Bucharest, Romania.
Anne BannuscherDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), 10589 Berlin, Germany.
Bryan HellackInstitute of Energy and Environmental Technology (IUTA) e.V., 47229 Duisburg, Germany.
Andrea HaaseDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), 10589 Berlin, Germany.ORCID 0000-0002-5288-7876
Sónia FragaEPIUnit-Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas, 4050-600 Porto, Portugal.
João Paulo TeixeiraEPIUnit-Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas, 4050-600 Porto, Portugal.ORCID 0000-0001-8693-5250
Universidade do Porto · PTUniversity of Bucharest · ROUniversity of Namur · BEStratiCELL (Belgium) · BEFederal Institute for Risk Assessment · DEGerman Environment Agency · DEUniversity of Fribourg · CH

Funding

Bundesinstitut für Risikobewertung 1329-561Fundação para a Ciência e a Tecnologia SFRH/BD/101060/2014Fundação para a Ciência e a Tecnologia SFRH/BD/12046/2016Fundação para a Ciência e a Tecnologia SIINN/0001/2013Fundação para a Ciência e a Tecnologia UIDB/04750/2020
6 · The paper itself

Abstract

Several reports on amorphous silica nanomaterial (aSiO

Indexed as

DNA damagegene expressionin vivo inhalationin vivo instillationrat lungsilica nanomaterials

Identifiers

PMID34200147
PMCPMC8228975
OpenAlexW3172450299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.