Evidence map›Paper›PMID 34200108›Full record

ReviewFoods (Basel, Switzerland)2021

Co-Encapsulated Synbiotics and Immobilized Probiotics in Human Health and Gut Microbiota Modulation.

Monika Kvakova, Izabela Bertkova, Jana Stofilova, Tor C Savidge

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Monika KvakovaDepartment of Experimental Medicine, Faculty of Medicine, P.J. Safarik University in Kosice, Trieda SNP 1, 04011 Kosice, Slovakia.ORCID 0000-0002-9659-5584
Izabela BertkovaDepartment of Experimental Medicine, Faculty of Medicine, P.J. Safarik University in Kosice, Trieda SNP 1, 04011 Kosice, Slovakia.
Jana StofilovaDepartment of Experimental Medicine, Faculty of Medicine, P.J. Safarik University in Kosice, Trieda SNP 1, 04011 Kosice, Slovakia.ORCID 0000-0002-9409-4153
Tor C SavidgeDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA.

Funding

Agency of the Ministry of Economy of the Slovak Republic for the Structural Funds of EU ITMS 313012T288Agentúra Ministerstva Školstva, Vedy, Výskumu a Športu SR ITMS 313011V336Pavol Jozef Safarik University in Kosice, Slovakia VVGS-2020-1506Scientific Grant Agency of the Ministry of Education of Slovak Republic and Academy of Sciences VEGA 1/0393/20
6 · The paper itself

Abstract

Growing interest in the development of innovative functional products as ideal carriers for synbiotics, e.g., nutrient bars, yogurt, chocolate, juice, ice cream, and cheese, to ensure the daily intake of probiotics and prebiotics, which are needed to maintain a healthy gut microbiota and overall well-being, is undeniable and inevitable. This review focuses on the modern approaches that are currently being developed to modulate the gut microbiota, with an emphasis on the health benefits mediated by co-encapsulated synbiotics and immobilized probiotics. The impact of processing, storage, and simulated gastrointestinal conditions on the viability and bioactivity of probiotics together with prebiotics such as omega-3 polyunsaturated fatty acids, phytochemicals, and dietary fibers using various delivery systems are considered. Despite the proven biological properties of synbiotics, research in this area needs to be focused on the proper selection of probiotic strains, their prebiotic counterparts, and delivery systems to avoid suppression of their synergistic or complementary effect on human health. Future directions should lead to the development of functional food products containing stable synbiotics tailored for different age groups or specifically designed to fulfill the needs of adjuvant therapy.

Indexed as

co-encapsulated synbioticsgut microbiota modulationhealth benefitsimmobilized probioticsprebioticssynergism

Identifiers

PMID34200108
PMCPMC8230215

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.