Evidence map›Paper›PMID 34200034›Full record

ArticlePathogens (Basel, Switzerland)2021

Cystic Fibrosis Sputum Impairs the Ability of Neutrophils to Kill

Kayla Fantone, Samantha L Tucker, Arthur Miller, Ruchi Yadav, Eryn E Bernardy, Rachel Fricker, Arlene A Stecenko, Joanna B Goldberg, Balázs Rada

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Effect of Fullerenol CNanomaterials (Basel, Switzerland) · 2026
    Article
  2. Microbial and host innate immune factors affecting the persistence ofFrontiers in cellular and infection microbiology · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Short chain fatty acids reduce the respiratory burst of human neutrophils in response to cystic fibrosis isolates of Staphylococcus aureus.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2023
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kayla FantoneDepartment of Infectious Diseases, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602, USA.
Samantha L TuckerDepartment of Infectious Diseases, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602, USA.ORCID 0000-0002-4164-4764
Arthur MillerDepartment of Infectious Diseases, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602, USA.
Ruchi YadavDepartment of Infectious Diseases, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602, USA.
Eryn E BernardyDivision of Pulmonology, Allergy/Immunology, Cystic Fibrosis and Sleep, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Rachel FrickerDepartment of Infectious Diseases, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602, USA.
Arlene A StecenkoDivision of Pulmonology, Allergy/Immunology, Cystic Fibrosis and Sleep, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Joanna B GoldbergDivision of Pulmonology, Allergy/Immunology, Cystic Fibrosis and Sleep, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Balázs RadaDepartment of Infectious Diseases, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602, USA.
University of Georgia · USEmory University · US

Funding

Neutrophil extracellular traps in cystic fibrosisR01HL136707 · NHLBI · UNIVERSITY OF GEORGIA · PI RADA, BALAZS · 2018 to 2021
$2.6M
Cystic Fibrosis Foundation MCCART15R0NHLBI NIH HHS R01 HL136707NIH HHS 5R01HL136707; UL1TR002378
6 · The paper itself

Abstract

Cystic fibrosis (CF) airway disease is characterized by chronic microbial infections and infiltration of inflammatory polymorphonuclear (PMN) granulocytes.

Indexed as

cystic fibrosiskillingneutrophil extracellular trapsPMNrespiratory burstsputumStaphylococcus aureus

Identifiers

PMID34200034
PMCPMC8229215
OpenAlexW3169527308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.