Evidence map›Paper›PMID 34199928›Full record

ArticleInternational journal of molecular sciences2021

Identification of Fucosylated SERPINA1 as a Novel Plasma Marker for Pancreatic Cancer Using Lectin Affinity Capture Coupled with iTRAQ-Based Quantitative Glycoproteomics.

Chia-Chun Wu, Yu-Ting Lu, Ta-Sen Yeh, Yun-Hsin Chan, Srinivas Dash, Jau-Song Yu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Plasma/Serum Proteomics based on Mass Spectrometry.Protein and peptide letters · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Chia-Chun WuMolecular Medicine Research Center, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0001-7684-1285
Yu-Ting LuMolecular Medicine Research Center, Chang Gung University, Taoyuan 33302, Taiwan.
Ta-Sen YehDepartment of General Surgery, Chang Gung Memorial Hospital, Linkou 33305, Taiwan.
Yun-Hsin ChanDepartment of General Surgery, Chang Gung Memorial Hospital, Linkou 33305, Taiwan.
Srinivas DashGraduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Jau-Song YuMolecular Medicine Research Center, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0002-4295-983X
Chang Gung University · TWChang Gung Memorial Hospital · TWChang Gung University of Science and Technology · TW

Funding

Chang Gung Memorial Hospital, Taiwan CLRPD1J0012Chang Gung Memorial Hospital, Taiwan CMRPD1H0253Ministry of Science and Technology, Taiwan MOST 109-2320-B-182-009-MY3
6 · The paper itself

Abstract

Pancreatic cancer (PC) is an aggressive cancer with a high mortality rate, necessitating the development of effective diagnostic, prognostic and predictive biomarkers for disease management. Aberrantly fucosylated proteins in PC are considered a valuable resource of clinically useful biomarkers. The main objective of the present study was to identify novel plasma glycobiomarkers of PC using the iTRAQ quantitative proteomics approach coupled with

Indexed as

alpha 1-AntitrypsinBiomarkers, TumorCase-Control StudiesChromatography, AffinityFemaleFucoseGlycoproteinsHumansLectinsMaleMass SpectrometryMiddle AgedPancreatic NeoplasmsProteomeSurvival Ratealpha 1-AntitrypsinBiomarkers, TumorFucoseGlycoproteinslectin, Aleuria aurantiaLectinsProteomeSERPINA1 protein, humanAALfucosylated SERPINA1glycobiomarkeriTRAQ-based quantitative proteomepancreatic cancerplasmareverse lectin-based ELISA

Identifiers

PMID34199928
PMCPMC8200073
OpenAlexW3170586139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.