Evidence map›Paper›PMID 34199855›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

A Wirelessly Controlled Scalable 3D-Printed Microsystem for Drug Delivery.

Farzad Forouzandeh, Nuzhet N Ahamed, Xiaoxia Zhu, Parveen Bazard, Krittika Goyal, Joseph P Walton, Robert D Frisina, David A Borkholder

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Farzad ForouzandehDepartment of Microsystems Engineering, Rochester Institute of Technology, Rochester, NY 14623, USA.
Nuzhet N AhamedDepartment of Microsystems Engineering, Rochester Institute of Technology, Rochester, NY 14623, USA.
Xiaoxia ZhuDepartment of Medical Engineering, Global Center for Hearing & Speech Research, University of South Florida, Tampa, FL 33620, USA.
Parveen BazardDepartment of Medical Engineering, Global Center for Hearing & Speech Research, University of South Florida, Tampa, FL 33620, USA.ORCID 0000-0001-8729-6112
Krittika GoyalDepartment of Microsystems Engineering, Rochester Institute of Technology, Rochester, NY 14623, USA.
Joseph P WaltonDepartment of Medical Engineering, Global Center for Hearing & Speech Research, University of South Florida, Tampa, FL 33620, USA.
Robert D FrisinaDepartment of Medical Engineering, Global Center for Hearing & Speech Research, University of South Florida, Tampa, FL 33620, USA.
David A BorkholderDepartment of Microsystems Engineering, Rochester Institute of Technology, Rochester, NY 14623, USA.

Funding

Enabling Microsystem Technologies for Advanced Drug DeliveryR01DC014568 · NIDCD · ROCHESTER INSTITUTE OF TECHNOLOGY · PI BORKHOLDER, DAVID A, FRISINA, ROBERT D · 2015 to 2019
$2.7M
NIDCD NIH HHS R01 DC014568
6 · The paper itself

Abstract

Here we present a 3D-printed, wirelessly controlled microsystem for drug delivery, comprising a refillable microreservoir and a phase-change peristaltic micropump. The micropump structure was inkjet-printed on the back of a printed circuit board around a catheter microtubing. The enclosure of the microsystem was fabricated using stereolithography 3D printing, with an embedded microreservoir structure and integrated micropump. In one configuration, the microsystem was optimized for murine inner ear drug delivery with an overall size of 19 × 13 × 3 mm

Indexed as

3D printingdrug deliveryimplantablemicropumpmicroreservoirtransdermal

Identifiers

PMID34199855
PMCPMC8227156

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.