ArticleCancers2021
Motor Evoked Potential Warning Criteria in Supratentorial Surgery: A Scoping Review.
Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06480370 (Optimization of Transcranial Motor Evoked Potentials in Supratentorial Surgeries), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Optimization of Transcranial Motor Evoked Potentials in Supratentorial Surgeries
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Diffusion tensor imaging versus intraoperative subcortical mapping for glioma resection: a systematic review and meta-analysis.Neurosurgical review · 2023Pooled it
- Effect of low-concentration sevoflurane with propofol anesthesia on transcranial motor-evoked potential: a crossover interventional trial.Journal of anesthesia · 2026Article
- Subcortical brain mapping strategies for intraoperative identification of the optic radiation during asleep and awake surgery: a scoping review.Brain & spine · 2026Review
- Explainable AI for Intraoperative Motor-Evoked Potential Muscle Classification in Neurosurgery: Bicentric Retrospective Study.Journal of medical Internet research · 2025Article
- Does persistent crossover (ipsilateral) motor evoked potential (MEP) responses represent a technical failure for intracranial motor tract monitoring? A case example and practical solution.Acta neurochirurgica · 2024Article
- Bayesian networks for Risk Assessment and postoperative deficit prediction in intraoperative neurophysiology for brain surgery.Journal of clinical monitoring and computing · 2024Article
- Intraoperative glioblastoma surgery-current challenges and clinical trials: An update.Cancer pathogenesis and therapy · 2024Review
- An ontology-based tool for modeling and documenting events in neurosurgery.BMC medical informatics and decision making · 2024Article
- Technical note: pre-positioning lower limb SSEP during semi-sitting positioning in posterior fossa surgery- does it matter?Journal of clinical monitoring and computing · 2023Article
- Opportunities and challenges of supervised machine learning for the classification of motor evoked potentials according to muscles.BMC medical informatics and decision making · 2023Article
- Total Intravenous Anesthesia Protocol for Decreasing Unacceptable Movements during Cerebral Aneurysm Clipping with Motor-Evoked Potential Monitoring: A Historical Control Study and Meta-Analysis.Journal of personalized medicine · 2023Article
- Application of Intraoperative Electromyography Intelligent Monitoring in Orthopedic Surgery under General Anesthesia.Contrast media & molecular imaging · 2023Article
- Current Status of Neuromodulation-Induced Cortical Prehabilitation and Considerations for Treatment Pathways in Lower-Grade Glioma Surgery.Life (Basel, Switzerland) · 2022Review
- Transcranial versus direct electrical stimulation for intraoperative motor-evoked potential monitoring: Prognostic value comparison in asleep brain tumor surgery.Frontiers in oncology · 2022Article
- Continuous subcortical language mapping in awake glioma surgery.Frontiers in oncology · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During intraoperative monitoring of motor evoked potentials (MEP), heterogeneity across studies in terms of study populations, intraoperative settings, applied warning criteria, and outcome reporting exists. A scoping review of MEP warning criteria in supratentorial surgery was conducted in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). Sixty-eight studies fulfilled the eligibility criteria. The most commonly used alarm criteria were MEP signal loss, which was always a major warning sign, followed by amplitude reduction and threshold elevation. Irreversible MEP alterations were associated with a higher number of transient and persisting motor deficits compared with the reversible changes. In almost all studies, specificity and Negative Predictive Value (NPV) were high, while in most of them, sensitivity and Positive Predictive Value (PPV) were rather low or modest. Thus, the absence of an irreversible alteration may reassure the neurosurgeon that the patient will not suffer a motor deficit in the short-term and long-term follow-up. Further, MEPs perform well as surrogate markers, and reversible MEP deteriorations after successful intervention indicate motor function preservation postoperatively. However, in future studies, a consensus regarding the definitions of MEP alteration, critical duration of alterations, and outcome reporting should be determined.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.