Evidence map›Paper›PMID 34199838›Full record

ArticleToxins2021

Anti-Cancer Effect of Moroccan Cobra

Ayoub Lafnoune, Su-Yeon Lee, Jin-Yeong Heo, Imane Gourja, Bouchra Darkaoui, Zaineb Abdelkafi-Koubaa, Fatima Chgoury, Khadija Daoudi, Salma Chakir, Rachida Cadi and 6 more

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Anticancer potency of Egyptian venom snakes on MCF-7 and HepG2 carcinoma cells.Environmental analysis, health and toxicology · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Anti-Cancer Activity ofMolecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 3 countries.

Ayoub LafnouneLaboratoire des Venins et Toxines, Département de Recherche, Institut Pasteur du Maroc, 1, Place Louis Pasteur, Casablanca 20360, Morocco.ORCID 0000-0003-0303-8525
Su-Yeon LeeCancer Biology Research Laboratory, Institut Pasteur Korea, 16, Daewangpangyo-ro 712 beon-gil Bundang-gu, Seong-nam-si 13488, Gyeonggi-do, Korea.
Jin-Yeong HeoScreening Discovery Platform, Institut Pasteur Korea, 16, Daewangpangyo-ro 712 beon-gil Bundang-gu, Seong-nam-si 13488, Gyeonggi-do, Korea.
Imane GourjaLaboratoire des Venins et Toxines, Département de Recherche, Institut Pasteur du Maroc, 1, Place Louis Pasteur, Casablanca 20360, Morocco.
Bouchra DarkaouiLaboratoire des Venins et Toxines, Département de Recherche, Institut Pasteur du Maroc, 1, Place Louis Pasteur, Casablanca 20360, Morocco.
Zaineb Abdelkafi-KoubaaLaboratoire des Venins et Biomolécules Thérapeutiques LR11IPT08, Institut Pasteur de Tunis, 13, Place Pasteur, Tunis 1002, Tunisia.
Fatima ChgouryLaboratoire des Venins et Toxines, Département de Recherche, Institut Pasteur du Maroc, 1, Place Louis Pasteur, Casablanca 20360, Morocco.
Khadija DaoudiLaboratoire des Venins et Toxines, Département de Recherche, Institut Pasteur du Maroc, 1, Place Louis Pasteur, Casablanca 20360, Morocco.
Salma ChakirLaboratoire des Venins et Toxines, Département de Recherche, Institut Pasteur du Maroc, 1, Place Louis Pasteur, Casablanca 20360, Morocco.
Rachida CadiLaboratoire Physiopathologie, Génétique Moléculaire & Biotechnologie, Faculté des Sciences Ain-Chock, Hassan II University of Casablanca, B.P 5366 Maarif, Casablanca 20000, Morocco.
Khadija MounajiLaboratoire Physiopathologie, Génétique Moléculaire & Biotechnologie, Faculté des Sciences Ain-Chock, Hassan II University of Casablanca, B.P 5366 Maarif, Casablanca 20000, Morocco.
Najet Srairi-AbidLaboratoire des Venins et Biomolécules Thérapeutiques LR11IPT08, Institut Pasteur de Tunis, 13, Place Pasteur, Tunis 1002, Tunisia.
Naziha MarrakchiLaboratoire des Venins et Biomolécules Thérapeutiques LR11IPT08, Institut Pasteur de Tunis, 13, Place Pasteur, Tunis 1002, Tunisia.
David ShumScreening Discovery Platform, Institut Pasteur Korea, 16, Daewangpangyo-ro 712 beon-gil Bundang-gu, Seong-nam-si 13488, Gyeonggi-do, Korea.
Haeng-Ran SeoCancer Biology Research Laboratory, Institut Pasteur Korea, 16, Daewangpangyo-ro 712 beon-gil Bundang-gu, Seong-nam-si 13488, Gyeonggi-do, Korea.
Naoual OukkacheLaboratoire des Venins et Toxines, Département de Recherche, Institut Pasteur du Maroc, 1, Place Louis Pasteur, Casablanca 20360, Morocco.
Institut Pasteur du Maroc · MAInstitut Pasteur Korea · KRInstitut Pasteur de Tunis · TNUniversity of Hassan II Casablanca · MA

Funding

Institut Pasteur Korea 2017M3A9G7072864 and NRF-2017M3A9G6068246
6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is the most common primary liver cancer in adults, the fifth most common malignancy worldwide and the third leading cause of cancer related death. An alternative to the surgical treatments and drugs, such as sorafenib, commonly used in medicine is necessary to overcome this public health problem. In this study, we determine the anticancer effect on HCC of Moroccan cobra

Indexed as

Naja hajeAnimalsAntineoplastic AgentsCarcinoma, HepatocellularCell Culture TechniquesCells, CulturedDose-Response Relationship, DrugElapid VenomsHepatocytesHumansLiver NeoplasmsAntineoplastic AgentsElapid Venomsanticancer moleculesHepatocellular carcinomamulticellular tumor spheroidsNaja hajevenom

Identifiers

PMID34199838
PMCPMC8229680
OpenAlexW3166911053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.