ArticleMaterials (Basel, Switzerland)2021
A Comparative Evaluation of Nanohydroxyapatite-Enriched Hydrogen Peroxide Home Bleaching System on Color, Hardness and Microstructure of Dental Enamel.
Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Evaluation of tooth sensitivity and whitening effects of tooth whitening agents containing calcium, hydroxyapatite and fluoride.Odontology · 2026Article
- Effects of bleaching agents containing nano-hydroxyapatite on sound and demineralized enamel: an in vitro study.Odontology · 2026Article
- Enamel and Bleaching or Breaching: Vickers Hardness and Backscattered Electron Imaging.Calcified tissue international · 2026Review
- Effect of a Home Bleaching Gel Containing Chitosan and Theobromine on Tooth Surface Roughness, Microhardness, and Colour Change.Gels (Basel, Switzerland) · 2025Article
- Advancements in nanohydroxyapatite: synthesis, biomedical applications and composite developments.Regenerative biomaterials · 2025Review
- Effect of incorporation of calcium polyphosphate sub-microparticles in low-concentration bleaching gels on physical properties of dental enamel.Odontology · 2024Article
- Tooth whitening: current status and prospects.Odontology · 2024Review
- Nanohydroxyapatite in dentistry: A comprehensive review.The Saudi dental journal · 2023Article
- Assessment of the Remineralizing Potential of Biomimetic Materials on Early Artificial Caries Lesions after 28 Days: An In Vitro Study.Bioengineering (Basel, Switzerland) · 2023Article
- Manganese oxide increases bleaching efficacy and reduces the cytotoxicity of a 10% hydrogen peroxide bleaching gel.Clinical oral investigations · 2022Article
- Novel Trends in Dental Color Match Using Different Shade Selection Methods: A Systematic Review and Meta-Analysis.Materials (Basel, Switzerland) · 2022Review
- Preparation and In Vitro Characterization of Gels Based on Bromelain, Whey and Quince Extract.Gels (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
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Abstract
This study aimed to evaluate two hydrogen peroxide (HP)-based at-home bleaching systems in order to analyze whether nano-hydroxyapatite (nHA) addition may represent a reliable and safe solution for tooth whitening without altering dental microstructure and hardness. Human third molars (N = 15) were treated with two bleaching agents, one containing 6%HP (6HP) and the other 6% HP nHA-enriched (6HP-nHA) with average particle diameter ranging from 5-20 nm. Their effects on enamel were assessed using a spectrophotometer, Vickers microhardness (VMH) test and Scanning Electron Microscopy (SEM), comparing the treated groups with the non-treated control group (CTR). Color analysis revealed improvement in whiteness in both groups compared to CTR. VMH test results showed no differences among the groups. SEM analysis highlighted no evident changes in the enamel microstructure of tested groups compared to CTR. At high magnification, in 6HP group, a slight increase in irregularities of enamel surface morphology was observed, while 6HP-nHA group displayed removal of the aprismatic layer but preservation of the intact prismatic structure. These results suggest that the 6HP-nHA agent may be recommended to provide reliable whitening treatment, without damaging the enamel micromorphology and hardness.
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