Evidence map›Paper›PMID 34199694›Full record

ArticleCurrent oncology (Toronto, Ont.)2021

The Screening and COnsensus Based on Practices and Evidence (SCOPE) Program-Results of a Survey on Daily Practice Patterns for Patients with mCRC.

Gerald Prager, Claus-Henning Köhne, Juan Manuel O'Connor, Fernando Rivera, Daniele Santini, Harpreet Wasan, Jean Marc Phelip

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 7 countries.

Gerald PragerDepartment of Medicine, Medical University of Vienna, 1090 Vienna, Austria.
Claus-Henning KöhneInnere Medizin-Onkologie und Hämatologie, Klinikum Oldenburg, 26133 Oldenburg, Germany.
Juan Manuel O'ConnorDepartment of Clinical Oncology, Instituto Alexander Fleming, Buenos Aires C1426ANZ, Argentina.ORCID 0000-0002-6975-5466
Fernando RiveraDepartment of Medical Oncology, University Hospital Marqués de Valdecilla, IDIVAL, 39008 Santander, Spain.
Daniele SantiniDepartment of Medical Oncology, Policlinico Universitario Campus Bio-Medico Rome, 00128 Rome, Italy.
Harpreet WasanDepartment of Cancer Medicine, Hammersmith Hospital, London SW7 2AZ, UK.
Jean Marc PhelipDepartment of Hepato-Gastroenterology, University Hospital of Saint-Étienne, 42270 Saint-Étienne-Priest-en-Jarez, France.
Campus Bio Medico University Hospital · ITCentre Hospitalier Universitaire de Saint-Étienne · FRHammersmith Hospital · GBInstituto Alexander Fleming · ARKlinikum Oldenburg · DEMarqués de Valdecilla University Hospital · ESMedical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The SCOPE project aimed to better understand practice patterns, identify drivers for treatment goals, and determine third- and fourth-line treatment choices for patients with metastatic colorectal cancer (mCRC). The survey was developed by an expert panel of gastrointestinal oncologists. Questions concerned general practice patterns, and treatment decisions for three hypothetical patient case scenarios. Participants had to routinely manage patients with mCRC. We present results from 629 participants who provided input on patient treatment scenarios (data cutoff: 17/01/2020). Prolonging overall survival (OS; 51%) was the main aim in first line. In third line, quality of life (QOL) was the primary goal (34%). Forty-three percent also cited efficacy-focused goals; 18% and 13% noted prolonging OS and improving progression-free survival as main aims, respectively. For fit and active patients, 89% of respondents considered trifluridine-tipiracil an appropriate third-line treatment; regorafenib (31%) or clinical trial enrollment (29%) were the fourth-line options. For patients with comorbidities and limited caregiver support, trifluridine-tipiracil was the preferred third-line treatment (70%). For

Indexed as

Colorectal NeoplasmsQuality of LifeAntineoplastic Combined Chemotherapy ProtocolsConsensusHumansPractice Guidelines as TopicSurveys and QuestionnairesKRAS-mutated mCRCKRAS-wildtype mCRCmetastatic colorectal cancerpractice patternsregorafenibtrifluridine-tipiracil

Identifiers

PMID34199694
PMCPMC8293190
OpenAlexW3169153828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.