Evidence map›Paper›PMID 34199668›Full record

ArticleMolecules (Basel, Switzerland)2021

Anti-Inflammatory and Anti-Diabetic Effect of Black Soybean Anthocyanins: Data from a Dual Cooperative Cellular System.

Jin-Nam Kim, Sung Nim Han, Hye-Kyeong Kim

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jin-Nam KimDepartment of Food Science & Nutrition, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon 14662, Korea.
Sung Nim HanDepartment of Food and Nutrition, Seoul National University, 1Gwanak-ro, Gwanak-gu, Seoul 08826, Korea.ORCID 0000-0003-0647-2992
Hye-Kyeong KimDepartment of Food Science & Nutrition, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon 14662, Korea.ORCID 0000-0003-1659-1709
Catholic University of Korea · KRSeoul National University · KR

Funding

Rural Development Administration PJ0071862011
6 · The paper itself

Abstract

Obesity is characterized by elevated infiltration of macrophages into adipose tissue, leading to the development of insulin resistance. The black soybean seed coat is a rich source of anthocyanins with antioxidative and anti-inflammatory activities. This study investigated the effects of black soybean anthocyanin extract (BSAn) on obesity-induced oxidative stress, the inflammatory response, and insulin resistance in a coculture system of hypertrophied 3T3-L1 adipocytes and RAW264 macrophages. Coculture of adipocytes with macrophages increased the production of reactive oxygen species and inflammatory mediators and cytokines (NO, MCP-1, PGE

Indexed as

3T3-L1 CellsAnimalsAnthocyaninsAnti-Inflammatory AgentsCell CommunicationCoculture TechniquesCytokinesGene Expression RegulationGlycine maxHypoglycemic AgentsInsulin ResistanceMiceRAW 264.7 CellsReactive Oxygen SpeciesSignal TransductionAnthocyaninsAnti-Inflammatory AgentsCytokinesHypoglycemic AgentsReactive Oxygen Speciesadipocyteinflammationinsulin resistancemacrophage

Identifiers

PMID34199668
PMCPMC8199741
OpenAlexW3167400776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.