Evidence map›Paper›PMID 34199600›Full record

ArticleViruses2021

Prevalence of Orthohantavirus-Reactive Antibodies in Humans and Peri-Domestic Rodents in Northern Ethiopia.

Yonas Meheretu, Åsa Granberg, Gebregiorgis Berhane, Hussein Khalil, Olivia Wesula Lwande, Mengistu Mitiku, Kiros Welegerima, Joëlle Goüy de Bellocq, Josef Bryja, Hagos Abreha and 3 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Yonas MeheretuDepartment of Biology, Mekelle University, Mekelle P.O. Box 3102, Ethiopia.ORCID 0000-0002-5406-1672
Åsa GranbergDepartment of Epidemiology and Global Health, Umeå University, 901 85 Umeå, Sweden.
Gebregiorgis BerhaneDepartment of Biology, Mekelle University, Mekelle P.O. Box 3102, Ethiopia.
Hussein KhalilDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, 901 83 Umeå, Sweden.
Olivia Wesula LwandeDepartment of Clinical Microbiology, Virology, Umeå University, 901 85 Umeå, Sweden.
Mengistu MitikuCollege Health Sciences, Mekelle University, Mekelle P.O. Box 231, Ethiopia.
Kiros WelegerimaDepartment of Biology, Mekelle University, Mekelle P.O. Box 3102, Ethiopia.
Joëlle Goüy de BellocqInstitute of Vertebrate Biology of the Czech Academy of Sciences, 603 65 Brno, Czech Republic.
Josef BryjaInstitute of Vertebrate Biology of the Czech Academy of Sciences, 603 65 Brno, Czech Republic.
Hagos AbrehaCollege Health Sciences, Mekelle University, Mekelle P.O. Box 231, Ethiopia.
Herwig LeirsEvolutionary Ecology Group, University of Antwerp, 2610 Wilrijk, Belgium.ORCID 0000-0002-7612-5024
Frauke EckeDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, 901 83 Umeå, Sweden.ORCID 0000-0003-4208-345X
Magnus EvanderDepartment of Clinical Microbiology, Virology, Umeå University, 901 85 Umeå, Sweden.
Mekelle University · ETUmeå University · SECzech Academy of Sciences, Institute of Vertebrate Biology · CZSwedish University of Agricultural Sciences · SECzech University of Life Sciences Prague · CZUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2012, Tigray orthohantavirus was discovered in Ethiopia, but its seasonal infection in small mammals, and whether it poses a risk to humans was unknown. The occurrence of small mammals, rodents and shrews, in human inhabitations in northern Ethiopia is affected by season and presence of stone bunds. We sampled small mammals in two seasons from low- and high-density stone bund fields adjacent to houses and community-protected semi-natural habitats in Atsbi and Hagere Selam, where Tigray orthohantavirus was first discovered. We collected blood samples from both small mammals and residents using filter paper. The presence of orthohantavirus-reactive antibodies in blood was then analyzed using immunofluorescence assay (human samples) and enzyme linked immunosorbent assays (small mammal samples) with Puumala orthohantavirus as antigen. Viral RNA was detected by RT-PCR using small mammal blood samples. Total orthohantavirus prevalence (antibodies or virus RNA) in the small mammals was 3.37%. The positive animals were three

Indexed as

AnimalsAntibodies, ViralCross-Sectional StudiesDisease ReservoirsEthiopiaFemaleHantavirus InfectionsHumansImmunoglobulin GMaleOrthohantavirusPrevalenceRatsRisk FactorsRNA, ViralRural PopulationAntibodies, ViralImmunoglobulin GRNA, ViralEthiopiaorthohantavirusrisk factorsrodentsrural community

Identifiers

PMID34199600
PMCPMC8226976
OpenAlexW3168696786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.