ArticleJournal of clinical medicine2021
The Association of Post-Concussion and Post-Traumatic Stress Disorder Symptoms with Health-Related Quality of Life, Health Care Use and Return-to-Work after Mild Traumatic Brain Injury.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Action Collaborative on Traumatic Brain Injury Care: Adapted Clinical Practice Guideline.Annals of family medicine · 2025Guideline
- The Relationship between Post-Traumatic Stress Disorder Due to Brain Injury and Glutamate Intake: A Systematic Review.Nutrients · 2024Pooled it
- Diagnostic Accuracy of Mental Health Screening Tools After Mild Traumatic Brain Injury.JAMA network open · 2024Trial
- Rehabilitation and outcomes after complicated vs uncomplicated mild TBI: results from the CENTER-TBI study.BMC health services research · 2022Trial
- Mobile Health App for Adults with Persisting Postconcussion Symptoms: Development and Usability Study.JMIR human factors · 2025Article
- Prognostic models for depression and post-traumatic stress disorder symptoms following traumatic brain injury: a CENTER-TBI study.BMJ mental health · 2025Observational
- Mild traumatic brain injury increases vulnerability to post-traumatic stress disorder in rats and the possible role of hippocampal DNA methylation.Frontiers in behavioral neuroscience · 2025Article
- Patient satisfaction with rehabilitation services following traumatic brain injury: a quality registry study.Journal of rehabilitation medicine · 2024Article
- Impact of traumatic brain injury on risk for schizophrenia and bipolar disorder.Psychiatry research · 2024Article
- Article
- Longitudinal Internal Validity of the Quality of Life after Brain Injury: Response Shift and Responsiveness.Journal of clinical medicine · 2023Article
- Traumatic brain injury: progress and challenges in prevention, clinical care, and research.The Lancet. Neurology · 2022Review
- Sex differences in outcomes from mild traumatic brain injury eight years post-injury.PloS one · 2022Article
- The Role of Mental Adjustment in Mediating Post-Traumatic Stress Disorder Symptoms and Social Support in Chinese Ovarian Cancer Patients: A Cross-Sectional Study.Psychology research and behavior management · 2022Article
- Analyzing the Spectrum of mTBI Subgroups.Neurotrauma reportsReview
- Persistent Symptom Burden Following Mild Traumatic Brain Injury Is Associated With Lower Quality of Life in Middle-Aged and Older Adults.Neurotrauma reportsArticle
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 3 countries.
Funding
Abstract
Patients with mild traumatic brain injury (mTBI) are at risk for post-concussion (PC) symptoms and post-traumatic stress disorder (PTSD). The co-occurrence of PC and PTSD symptoms after mTBI in relation to health-related quality of life (HRQoL), health care utilization, and return to work has not yet been investigated. PC and PTSD symptoms were measured six months post-TBI by respectively the Rivermead Post-Concussion Symptoms Questionnaire (RPQ) and the Post-Traumatic Stress Disorder Checklist for DSM-5 (PCL-5). Of the 1566 individuals after mTBI who met the inclusion criteria, 26.1% experienced PC symptoms (RPQ ≥16). Additionally, 9.8% experienced PTSD symptoms (PCL-5 ≥ 33), of which the vast majority (81%) also reported experiencing PC symptoms. Differences between patients with no/mild symptoms, with only PC, only PTSD, and both PC and PTSD symptoms in HRQoL, return to work, and rehabilitation were analyzed using logistic and linear regression analyses. Patients with PC and/or PTSD symptoms reported lower HRQoL, higher rates of rehabilitation, and lower return to work rates compared to patients with no/mild symptoms. Patients with both PC and PTSD symptoms reported significantly lower HRQoL (B = -2.73, CI = -4.65; -0.83,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.