Evidence map›Paper›PMID 34199547›Full record

ReviewInfectious disease reports2021

Diagnosis of Herpes Simplex Virus: Laboratory and Point-of-Care Techniques.

Peuli Nath, Md Alamgir Kabir, Somaiyeh Khoubafarin Doust, Aniruddha Ray

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Infectious disease reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Peuli NathDepartment of Physics and Astronomy, University of Toledo, Toledo, OH 43606, USA.ORCID 0000-0003-1285-0240
Md Alamgir KabirDepartment of Physics and Astronomy, University of Toledo, Toledo, OH 43606, USA.
Somaiyeh Khoubafarin DoustDepartment of Physics and Astronomy, University of Toledo, Toledo, OH 43606, USA.
Aniruddha RayDepartment of Physics and Astronomy, University of Toledo, Toledo, OH 43606, USA.ORCID 0000-0003-2561-2217

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes is a widespread viral infection caused by the herpes simplex virus (HSV) that has no permanent cure to date. There are two subtypes, HSV-1 and HSV-2, that are known to cause a variety of symptoms, ranging from acute to chronic. HSV is highly contagious and can be transmitted via any type of physical contact. Additionally, viral shedding can also happen from asymptomatic infections. Thus, early and accurate detection of HSV is needed to prevent the transmission of this infection. Herpes can be diagnosed in two ways, by either detecting the presence of the virus in lesions or the antibodies in the blood. Different detection techniques are available based on both laboratory and point of care (POC) devices. Laboratory techniques include different biochemical assays, microscopy, and nucleic acid amplification. In contrast, POC techniques include microfluidics-based tests that enable on-spot testing. Here, we aim to review the different diagnostic techniques, both laboratory-based and POC, their limits of detection, sensitivity, and specificity, as well as their advantages and disadvantages.

Indexed as

detectiondiagnosticsherpes simplex virusimaging and microscopymicrofluidicspoint-of-care devices

Identifiers

PMID34199547
PMCPMC8293188

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.