Evidence map›Paper›PMID 34199396›Full record

ArticleJournal of clinical medicine2021

Correlation between Potential Risk Factors and Pulmonary Embolism in Sarcoidosis Patients Timely Treated.

Barbara Ruaro, Paola Confalonieri, Mario Santagiuliana, Barbara Wade, Elisa Baratella, Metka Kodric, Maria Berria, Mohamad Jaber, Chiara Torregiani, Cosimo Bruni and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Autoantibodies in sarcoidosis: Innocent bystander or promising biomarker for organ involvement?Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2024
    Article
  3. Review
  4. Article
  5. The Symptoms of Pulmonary Sarcoidosis.Journal of clinical medicine · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. In Vivo Fibroblast Activation of Systemic Sarcoidosis: ADiagnostics (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Antiphospholipid Syndrome in Pregnancy: New and Old Pathogenetic Mechanisms.International journal of molecular sciences · 2023
    Review
  12. Review
  13. Observational
  14. Chronic Thromboembolic Pulmonary Hypertension: An Update.Diagnostics (Basel, Switzerland) · 2022
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Barbara RuaroDepartment of Pulmonology, University Hospital of Cattinara, 34127 Trieste, Italy.ORCID 0000-0001-8990-859X
Paola ConfalonieriDepartment of Pulmonology, University Hospital of Cattinara, 34127 Trieste, Italy.
Mario SantagiulianaDepartment of Pulmonology, University Hospital of Cattinara, 34127 Trieste, Italy.
Barbara WadeAOU City of Health and Science of Turin, Department of Science of Public Health and Pediatrics, University of Torino, 10126 Torino, Italy.
Elisa BaratellaDepartment of Radiology, Cattinara Hospital, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0002-1061-9507
Metka KodricDepartment of Pulmonology, University Hospital of Cattinara, 34127 Trieste, Italy.
Maria BerriaDepartment of Internal Medicine, University of Sassari, 07100 Sassari, Italy.
Mohamad JaberDepartment of Pulmonology, University Hospital of Cattinara, 34127 Trieste, Italy.
Chiara TorregianiDepartment of Pulmonology, University Hospital of Cattinara, 34127 Trieste, Italy.
Cosimo BruniDepartment of Experimental and Clinical Medicine, Division of Rheumatology, University of Firenze, 50121 Florence, Italy.ORCID 0000-0003-2813-2083
Marco ConfalonieriDepartment of Pulmonology, University Hospital of Cattinara, 34127 Trieste, Italy.ORCID 0000-0002-4791-768X
Francesco SaltonDepartment of Pulmonology, University Hospital of Cattinara, 34127 Trieste, Italy.ORCID 0000-0002-0864-9766
Ospedale di Cattinara · ITUniversity of Florence · ITUniversity of Sassari · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSome studies with inconclusive results have reported a link between sarcoidosis and an increased risk of pulmonary embolism (PE). This study aimed at assessing a possible correlation between potential risk factors and PE in sarcoidosis patients.

methodsA total of 256 sarcoidosis patients (84 males and 172 females; mean age at diagnosis 49 ± 13) were enrolled after giving written informed consent. Clinical evaluations, laboratory and radiology tests were performed to evaluate the presence of pulmonary embolism.

resultsFifteen sarcoidosis patients with PE (4 males and 11 females; mean age at diagnosis 50 ± 11), diagnosed by lung scintigraphy and 241 sarcoidosis patients without PE (80 males and 161 females; mean age at diagnosis 47 ± 13), were observed. There was a statistically significant increase of the presence of antiphospholipid antibodies in the sarcoidosis group with pulmonary embolism. There was no statistically significant difference between the two groups as to smoking habit, obesity or hereditary thrombophilia frequency (

conclusionsThis study demonstrates a significant correlation between the presence of antiphospholipid antibody positivity and the pulmonary embolism events in our sarcoidosis patients. Furthermore, we propose screening for these antibodies and monitoring, aimed at timely treatment.

Indexed as

antiphospholipid antibodiespulmonary embolismsarcoidosisscintigraphytimely treatment

Identifiers

PMID34199396
PMCPMC8199598
OpenAlexW3165958727

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.