Evidence map›Paper›PMID 34199272›Full record

ArticleJournal of personalized medicine2021

The Impact of SARS-CoV-2 Pandemic on the New Cases of T1DM in Children. A Single-Centre Cohort Study.

Anca Andreea Boboc, Carmen Nicoleta Novac, Maria Teodora Ilie, Mara Ioana Ieșanu, Felicia Galoș, Mihaela Bălgrădean, Elena Camelia Berghea, Marcela Daniela Ionescu

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Review
  8. Article
  9. Article
  10. Article
  11. Covid 19 and diabetes in children: advances and strategies.Diabetology & metabolic syndrome · 2024
    Review
  12. Type 1 Diabetes and COVID-19: A Literature Review and Possible Management.International journal of endocrinology and metabolism · 2023
    Review
  13. A Multifaced Aspect ofJournal of personalized medicine · 2023
    Review
  14. Review
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Personalized Medicine in Epidemics.Journal of personalized medicine · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anca Andreea BobocMarie Curie Emergency Children's Hospital, 041451 Bucharest, Romania.
Carmen Nicoleta NovacMarie Curie Emergency Children's Hospital, 041451 Bucharest, Romania.
Maria Teodora IlieMarie Curie Emergency Children's Hospital, 041451 Bucharest, Romania.ORCID 0000-0002-9263-7521
Mara Ioana IeșanuMarie Curie Emergency Children's Hospital, 041451 Bucharest, Romania.
Felicia GaloșMarie Curie Emergency Children's Hospital, 041451 Bucharest, Romania.
Mihaela BălgrădeanMarie Curie Emergency Children's Hospital, 041451 Bucharest, Romania.ORCID 0000-0003-3188-0330
Elena Camelia BergheaMarie Curie Emergency Children's Hospital, 041451 Bucharest, Romania.ORCID 0000-0001-9522-8363
Marcela Daniela IonescuMarie Curie Emergency Children's Hospital, 041451 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 1 diabetes mellitus (T1DM) represents one of the most frequent chronic illnesses affecting children. The early diagnosis of this disease is crucial, as it plays a key role in preventing the development of a life-threatening acute complication: diabetic ketoacidosis. The etiopathogenetic role of viral infections has long been suggested and emerging data are pointing towards a complex bidirectional relationship between diabetes and COVID-19. The aim of this study is to assess the impact of the COVID-19 pandemic on the incidence and severity of new T1DM cases in children in Romania. We analyzed the differences between a group of 312 patients diagnosed with T1DM in the period 2003-2019 and a group of 147 children diagnosed during the pandemic. The data were investigated using statistical analysis of a series of relevant variables. The total number of newly diagnosed T1DM increased by 30.08% in the period March 2020-February 2021 compared to the previous years. The patients in the pandemic group had a higher mean age at the onset of T1DM, were less frequently living in an urban area, and presented a higher mean value of HbA1c. Diabetic ketoacidosis at the onset of T1DM was 67.40% more frequent, and a higher percentage of these patients presented with a severe form. The duration of T1DM symptoms did not differ significantly between the two groups. A number of 8 patients associated SARS-CoV-2 infection at the time of T1DM diagnosis.

Indexed as

childrenCOVID-19diabetic ketoacidosisearly diagnosisepidemicstype 1 diabetes mellitus

Identifiers

PMID34199272
PMCPMC8231839

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.