Evidence map›Paper›PMID 34199205›Full record

ArticlePathogens (Basel, Switzerland)2021

Detection of Prions in Brain Homogenates and CSF Samples Using a Second-Generation RT-QuIC Assay: A Useful Tool for Retrospective Analysis of Archived Samples.

Tibor Moško, Soňa Galušková, Radoslav Matěj, Magdalena Brůžová, Karel Holada

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tibor MoškoInstitute of Immunology and Microbiology, First Faculty of Medicine, Charles University, 12800 Prague, Czech Republic.ORCID 0000-0002-4044-8155
Soňa GaluškováInstitute of Immunology and Microbiology, First Faculty of Medicine, Charles University, 12800 Prague, Czech Republic.
Radoslav MatějDepartment of Pathology and Molecular Medicine, Third Faculty of Medicine, Charles University and Thomayer University Hospital, 14059 Prague, Czech Republic.ORCID 0000-0002-6152-6343
Magdalena BrůžováDepartment of Pathology and Molecular Medicine, Third Faculty of Medicine, Charles University and Thomayer University Hospital, 14059 Prague, Czech Republic.ORCID 0000-0002-6603-7602
Karel HoladaInstitute of Immunology and Microbiology, First Faculty of Medicine, Charles University, 12800 Prague, Czech Republic.
Charles University · CZ

Funding

Agentura Pro Zdravotnický Výzkum České Republiky NV18-04-00179
6 · The paper itself

Abstract

The possibilities for diagnosing prion diseases have shifted significantly over the last 10 years. The RT-QuIC assay option has been added for neuropsychiatric symptoms, supporting biomarkers and final

Indexed as

archived sampleCJDCreutzfeldt-Jakob diseaseprion diseasesRT-QuIC assay

Identifiers

PMID34199205
PMCPMC8231989
OpenAlexW3169570805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.