ArticleBiology2021
A Procedure for Oxytocin Measurement in Hair of Pig: Analytical Validation and a Pilot Application.
Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- A systematic review of associations between hormone levels in hair and peripartum depression.Psychoneuroendocrinology · 2025Pooled it
- Severe claw lesions in pregnant sows reduce prolificacy and increase litter heterogeneity.Porcine health management · 2025Article
- Tracking Epidermal Cortisol and Oxytocin in Managed Bottlenose Dolphins as Potential Non-Invasive Physiological Welfare Indicators.Animals : an open access journal from MDPI · 2025Article
- Development of a Methodology for Measuring Oxytocin in Feces: Insights from a Preliminary Study in Captive Lions (Animals : an open access journal from MDPI · 2025Article
- The Oxytocin System and Implications for Oxytocin Deficiency in Hypothalamic-Pituitary Disease.Endocrine reviews · 2025Review
- Changes in hair cortisol and oxytocin independently associate with positive and negative psychological states in female soccer players.Frontiers in sports and active living · 2025Article
- Effects of oxytocin on the hair growth ability of dermal papilla cells.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
There is growing interest in oxytocin as a biomarker of stress and welfare. The objective of this study was to develop and validate a procedure based on a highly sensitive immunoassay to measure oxytocin in the hair of pigs. In addition, a pilot study to apply this procedure to evaluate possible changes in concentrations of oxytocin in hair during the reproductive cycle of pigs at different periods of the year was conducted. This procedure used methanol for sample extraction, since it offered better recoveries than acetonitrile, and the immunoassay developed was precise and accurate for the quantification of the oxytocin in the hair. When this procedure was applied to hair collected at different times of the reproductive cycle and season, higher values were found at days 23 and 59 after farrowing in the winter-spring period. In addition, higher oxytocin values in the spring-summer period were found in hair collected 5 days before farrowing compared to winter-spring. Oxytocin in hair showed moderate and low correlations with cortisone and cortisol in hair, respectively. This study represents the first report in which oxytocin was measured in hair and could open new lines for future research about the measurement of oxytocin in pigs and other biological species as a biomarker of stress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.