ReviewInternational journal of molecular sciences2021
Predictive Ability of Procalcitonin for Acute Kidney Injury: A Narrative Review Focusing on the Interference of Infection.
Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 32 citations in OpenAlex.
- The predictive value of early systemic inflammatory response index (SIRI), serum βRenal failure · 2026Article
- Evaluating the diagnostic and prognostic utility of serum DLL1 in acute-on-chronic liver failure patients with bacterial infections.Frontiers in medicine · 2026Article
- Prediction of hospital mortality in sepsis-associated acute kidney injury using a machine-learning approach: a multicenter study using SHAP interpretability analysis.Clinical kidney journal · 2026Article
- Persistent Severe Acute Kidney Injury Among Critically Ill Patients: Outcomes and Predictive Markers-A Single-Center Retrospective Cohort Study.Critical care research and practice · 2026Article
- Current and novel biomarkers in cardiogenic shock.European journal of heart failure · 2025Review
- An early warning model to predict acute kidney injury in sepsis patients with prior hypertension.Heliyon · 2024Article
- Study on the Predictive Value of Renal Resistive Index Combined with β2-Microglobulin in Patients with Urosepsis Complicated with Acute Kidney Injury.Journal of inflammation research · 2024Article
- Serum procalcitonin as a marker of neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD).Clinics (Sao Paulo, Brazil) · 2024Article
- Impact of recombinant human brain natriuretic peptide on emergency dialysis and prognosis in end-stage renal disease patients with type 4 cardiorenal syndrome.Scientific reports · 2023Article
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- Diagnostic and Prognostic Roles of C-Reactive Protein, Procalcitonin, and Presepsin in Acute Kidney Injury Patients Initiating Continuous Renal Replacement Therapy.Diagnostics (Basel, Switzerland) · 2023Article
- Increased Plasma Concentrations of Extracellular Vesicles Are Associated with Pro-Inflammatory and Pro-Thrombotic Characteristics of Left and Right Ventricle Mechanical Support Devices.Journal of cardiovascular development and disease · 2023Article
- Risk factors for BK virus infection in DCD donor kidney transplant recipients.Frontiers in medicine · 2023Article
- Construction and validation of an early warning model for predicting the acute kidney injury in elderly patients with sepsis.Aging clinical and experimental research · 2022Article
- The Role of Presepsin and Procalcitonin in Early Diagnosis of Bacterial Infections in Cirrhotic Patients with Acute-on-Chronic Liver Failure.Journal of clinical medicine · 2022Article
- The Role of Presepsin in Diagnosing Infections in Patients with Liver Cirrhosis and Overt Hepatic Encephalopathy.Diagnostics (Basel, Switzerland) · 2022Article
- A Predictive Model Based on Inflammatory and Coagulation Indicators for Sepsis-Induced Acute Kidney Injury.Journal of inflammation research · 2022Article
- The Monocyte-to-Lymphocyte Ratio Predicts Acute Kidney Injury After Acute Hemorrhagic Stroke.Frontiers in neurology · 2022Article
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Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Acute kidney injury (AKI) is a common yet complicated clinical entity with high morbidity and mortality. An essential strategy to improve AKI patients' prognoses is finding optimal biomarkers to identify AKI in a timely manner. Procalcitonin (PCT), a well-recognized biomarker for diagnosing infection and guiding antibiotics therapy, has been proposed to predict AKI development and recovery in many clinical settings. The current review provides comprehensive and updated information from relevant studies to evaluate PCT's AKI-predictive ability and the influence of infection on this predictive ability. PCT has demonstrated optimal predictive ability for AKI in various populations irrespective of infection. However, the predictive ability seems to be blunted by infection since infection and inflammation have a more potent influence than AKI on PCT elevation. We furthermore explain the complicated association between elevated PCT levels and AKI in infection and inflammation situations and recommend directions for further investigations to clarify the essential issue. In conclusion, although conflicting data exist, serum PCT level is a potential biomarker for predicting AKI in many clinical settings regardless of infection. Nevertheless, further studies are warranted to clarify the association between PCT, infection, and AKI and to confirm the utilization of PCT for AKI prediction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.