Evidence map›Paper›PMID 34199044›Full record

ArticleMedicina (Kaunas, Lithuania)2021

Cardiac Amyloidosis with Discordant QRS Voltage between Frontal and Precordial Leads.

Csilla-Andrea Eötvös, Roxana-Daiana Lazar, Iulia-Georgiana Zehan, Erna-Brigitta Lévay-Hail, Giorgia Pastiu, Mihaela Pop, Anca Simona Bojan, Sorin Pop, Dan Blendea

Abstract readCase Reports
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Csilla-Andrea Eötvös"Niculae Stancioiu" Heart Institute, 400001 Cluj-Napoca, Romania.
Roxana-Daiana LazarDepartment of Medicine, Faculty of Medicine, University of Medicine and Pharmacy "Iuliu Hatieganu", 400012 Cluj-Napoca, Romania.
Iulia-Georgiana ZehanDepartment of Medicine, Faculty of Medicine, University of Medicine and Pharmacy "Iuliu Hatieganu", 400012 Cluj-Napoca, Romania.
Erna-Brigitta Lévay-HailDepartment of Medicine, Faculty of Medicine, University of Medicine and Pharmacy "Iuliu Hatieganu", 400012 Cluj-Napoca, Romania.
Giorgia PastiuDepartment of Medicine, Faculty of Medicine, University of Medicine and Pharmacy "Iuliu Hatieganu", 400012 Cluj-Napoca, Romania.
Mihaela PopSchulich Heart Research Program, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.
Anca Simona BojanDepartment of Medicine, Faculty of Medicine, University of Medicine and Pharmacy "Iuliu Hatieganu", 400012 Cluj-Napoca, Romania.
Sorin PopDepartment of Medicine, Faculty of Medicine, University of Medicine and Pharmacy "Iuliu Hatieganu", 400012 Cluj-Napoca, Romania.
Dan BlendeaDepartment of Medicine, Faculty of Medicine, University of Medicine and Pharmacy "Iuliu Hatieganu", 400012 Cluj-Napoca, Romania.ORCID 0000-0002-4137-8582

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among the different types, immunoglobulin light chain (AL) cardiac amyloidosis is associated with the highest morbidity and mortality. The outcome, however, is significantly better when an early diagnosis is made and treatment initiated promptly. We present a case of cardiac amyloidosis with left ventricular hypertrophy criteria on the electrocardiogram. After 9 months of follow-up, the patient developed low voltage in the limb leads, while still maintaining the Cornell criteria for left ventricular hypertrophy as well. The relative apical sparing by the disease process, as well as decreased cancellation of the opposing left ventricular walls could be responsible for this phenomenon. The discordance between the voltage in the frontal leads and precordial leads, when present in conjunction with other findings, may be helpful in raising the clinical suspicion of cardiac amyloidosis.

Indexed as

AmyloidosisElectrocardiographyHeart VentriclesHumansHypertrophy, Left Ventricularamyloidosiscardiomyopathylow voltage

Identifiers

PMID34199044
PMCPMC8306315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.