Evidence map›Paper›PMID 34199041›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Interactions of Some Chemotherapeutic Agents as Epirubicin, Gemcitabine and Paclitaxel in Multicomponent Systems Based on Orange Essential Oil.

Adriana Samide, Bogdan Tutunaru, Renata-Maria Varut, Bogdan Oprea, Simona Iordache

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Adriana SamideChemistry Department, Faculty of Sciences, University of Craiova, Calea Bucuresti 107i, 200478 Craiova, Romania.
Bogdan TutunaruChemistry Department, Faculty of Sciences, University of Craiova, Calea Bucuresti 107i, 200478 Craiova, Romania.ORCID 0000-0002-2101-3391
Renata-Maria VarutFaculty of Pharmacy, University of Medicine and Pharmacy, Petru Rareş 2, 200349 Craiova, Romania.
Bogdan OpreaFaculty of Medicine, University of Medicine and Pharmacy, Petru Rareş 2, 200349 Craiova, Romania.
Simona IordacheChemistry Department, Faculty of Sciences, University of Craiova, Calea Bucuresti 107i, 200478 Craiova, Romania.
University of Craiova · ROUniversity of Medicine and Pharmacy of Craiova · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to anticipate the effect induced by a natural product on the chemical activity of medicines simultaneously administered, spontaneous interactions of certain cancer treatment drugs such as, epirubicin (EPR), gemcitabine (GCT), and paclitaxel (PTX) with limonene (LIM)-a natural compound extracted from orange peel and known as an anticancer agent-were investigated. To estimate the stability of the drugs over time, a current density of 50 mA cm

Indexed as

Autodock 4.2.6 systemchemotherapeuticsexperimental and kinetic studiesinteractionslimonenequantum chemical calculation

Identifiers

PMID34199041
PMCPMC8308819
OpenAlexW3177304424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.