Trial reportNutrients2021
The Effect of A Whey-Protein and Galacto-Oligosaccharides Based Product on Parameters of Sleep Quality, Stress, and Gut Microbiota in Apparently Healthy Adults with Moderate Sleep Disturbances: A Randomized Controlled Cross-Over Study.
Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The Microbiota-Gut-Brain Axis in Metabolic Syndrome and Sleep Disorders: A Systematic Review.Nutrients · 2024Pooled it
- The Therapeutic Impact of Plant-Based and Nutritional Supplements on Anxiety, Depressive Symptoms and Sleep Quality among Adults and Elderly: A Systematic Review of the Literature.International journal of environmental research and public health · 2023Pooled it
- Examining the Influence of the Human Gut Microbiota on Cognition and Stress: A Systematic Review of the Literature.Nutrients · 2022Pooled it
- Mulberry leaf extract combined with tryptophan improves sleep and post wake mood in adults with sleep complaints - A randomized cross-over study.European journal of nutrition · 2025Trial
- Effect of intravenous esketamine on postoperative sleep disturbance, anxiety, and depression in elderly patients undergoing laparoscopic abdominal surgery: a randomized controlled trial.BMC geriatrics · 2025Trial
- Trial
- The Gut Microbiome in Sleep Disorders: A Review of Recent Evidence.Actas espanolas de psiquiatria · 2026Review
- Maternal cardiovascular health and offspring neurodevelopment within the first five years of life: a birth cohort study.World journal of pediatrics : WJP · 2025Article
- The Consumption of Milk or Dairy Products and Sleep Quality: A Systematic Review and Meta-Analysis.Cureus · 2025Review
- Plasma biomarkers of dairy intake and gut microbiome, and their association with incident carotid plaque: a prospective cohort study.BMC medicine · 2025Article
- Article
- A double-blind intervention trial in healthy women demonstrates the beneficial impact onFrontiers in nutrition · 2024Article
- Sweet dreams are not made of this: no association between diet and sleep quality.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023Article
- Effect of Consumption of Animal Products on the Gut Microbiome Composition and Gut Health.Food science of animal resources · 2023Review
- Different Approaches to Ergogenic, Pre-, and Probiotic Supplementation in Sports with Different Metabolism Characteristics: A Mini Review.Nutrients · 2023Review
- Exploring the Role of Dairy Products In Sleep Quality: From Population Studies to Mechanistic Evaluations.Advances in nutrition (Bethesda, Md.) · 2023Review
- Gastrointestinal Effects and Tolerance of Nondigestible Carbohydrate Consumption.Advances in nutrition (Bethesda, Md.) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
People experiencing sleep problems may benefit from nutrients supporting serotonin metabolism and stress reduction. We studied the effect of a dairy-based product (DP) containing protein, galacto-oligosaccharides, vitamins and minerals, on sleep quality, stress, and gut-microbiota. In a cross-over RCT (three weeks intervention; three weeks washout), adults (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.