Evidence map›Paper›PMID 34198973›Full record

ReviewMicroorganisms2021

SARS-CoV-2 Portrayed against HIV: Contrary Viral Strategies in Similar Disguise.

Ralf Duerr, Keaton M Crosse, Ana M Valero-Jimenez, Meike Dittmann

Abstract readReview
In one paragraph

Review in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. RSC medicinal chemistry · 2023
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ralf DuerrDepartment of Microbiology, New York University School of Medicine, New York, NY 10016, USA.
Keaton M CrosseDepartment of Microbiology, New York University School of Medicine, New York, NY 10016, USA.
Ana M Valero-JimenezDepartment of Microbiology, New York University School of Medicine, New York, NY 10016, USA.
Meike DittmannDepartment of Microbiology, New York University School of Medicine, New York, NY 10016, USA.

Funding

Viral Evolution and Humoral Immune Response to Dual HIV-1 InfectionR01AI083142 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GORNY, MIROSLAW K · 2010 to 2015
$2.6M
Novel HIV-1 Env trimer probes for efficient isolation of broadly neutralizing antibodiesR01AI122953 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WU, XUELING · 2016 to 2019
$2.6M
ELF1 - Molecular mechanisms of a novel transcription factor with broad antiviral activityR01AI143639 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WEISER, JEFFREY NEAL · 2019 to 2023
$2.5M
Viral Evolution and Humoral Immune Response to Dual HIV-1 InfectionR56AI083142 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NYAMBI, PHILLIPE N · 2009 to 2009
$407k
Division of Intramural Research, National Institute of Allergy and Infectious Diseases R01AI143639G. Harold and Leila Y. Mathers Charitable Foundation To M.D.National Institute of Allergy and Infectious Diseases AI083142NIAID NIH HHS R01 AI122953NIAID NIH HHS R01 AI143639NYU Grossman School of Medicine Startup funds To M.D.
6 · The paper itself

Abstract

SARS-CoV-2 and HIV are zoonotic viruses that rapidly reached pandemic scale, causing global losses and fear. The COVID-19 and AIDS pandemics ignited massive efforts worldwide to develop antiviral strategies and characterize viral architectures, biological and immunological properties, and clinical outcomes. Although both viruses have a comparable appearance as enveloped viruses with positive-stranded RNA and envelope spikes mediating cellular entry, the entry process, downstream biological and immunological pathways, clinical outcomes, and disease courses are strikingly different. This review provides a systemic comparison of both viruses' structural and functional characteristics, delineating their distinct strategies for efficient spread.

Indexed as

COVID-19 and AIDS pandemicsHIVSARS-CoV-2viral entryzoonotic viruses

Identifiers

PMID34198973
PMCPMC8307803

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.