Evidence map›Paper›PMID 34198865›Full record

ReviewVaccines2021

Nano-Microparticle Platforms in Developing Next-Generation Vaccines.

Giuseppe Cappellano, Hugo Abreu, Chiara Casale, Umberto Dianzani, Annalisa Chiocchetti

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Giuseppe CappellanoDipartimento di Scienze della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0001-5193-4688
Hugo AbreuDipartimento di Scienze della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0003-4720-6519
Chiara CasaleDipartimento di Scienze della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100 Novara, Italy.
Umberto DianzaniDipartimento di Scienze della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100 Novara, Italy.
Annalisa ChiocchettiDipartimento di Scienze della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0002-4349-1087
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

Associazione Italiana per la Ricerca sul Cancro IG 20714Fondazione Cariplo 2017-0535Fondazione Cariplo 2019-3277Fondazione Italiana Sclerosi Multipla 2020/PR-Single/021Horizon 2020 Framework Programme 953121Italian Ministry of Education, University and Research (MIUR) program "Departments of Excellence 2018-2022", FOHN
6 · The paper itself

Abstract

The first vaccines ever made were based on live-attenuated or inactivated pathogens, either whole cells or fragments. Although these vaccines required the co-administration of antigens with adjuvants to induce a strong humoral response, they could only elicit a poor CD8

Indexed as

advanced vaccinesextracellular vesiclesliposomePLGAvirus infection

Identifiers

PMID34198865
PMCPMC8228777
OpenAlexW3170342439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.