Evidence map›Paper›PMID 34198717›Full record

ArticleViruses2021

Severe Fever with Thrombocytopenia Syndrome in Cats and Its Prevalence among Veterinarian Staff Members in Nagasaki, Japan.

Tsuyoshi Ando, Takeshi Nabeshima, Shingo Inoue, Mya Myat Ngwe Tun, Miho Obata, Weiyin Hu, Hiroshi Shimoda, Shintaro Kurihara, Koichi Izumikawa, Kouichi Morita and 1 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
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  5. Article
  6. Transboundary and emerging diseases · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. The public health threat of emerging phenuiviruses.One health (Amsterdam, Netherlands) · 2025
    Review
  13. Epidemiological Characteristics of Severe Fever with Thrombocytopenia Syndrome.The American journal of tropical medicine and hygiene · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Tsuyoshi AndoDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan.
Takeshi NabeshimaDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan.
Shingo InoueDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan.
Mya Myat Ngwe TunDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan.
Miho ObataLaboratory of Veterinary Microbiology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8511, Japan.
Weiyin HuLaboratory of Veterinary Microbiology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8511, Japan.
Hiroshi ShimodaLaboratory of Veterinary Microbiology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8511, Japan.
Shintaro KuriharaDepartment of Medical Safety, Nagasaki University Hospital, Nagasaki University, Nagasaki 852-8501, Japan.
Koichi IzumikawaInfection Control and Education Center, Nagasaki University Hospital, Nagasaki University, Nagasaki 852-8501, Japan.
Kouichi MoritaDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan.
Daisuke HayasakaLaboratory of Veterinary Microbiology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8511, Japan.
Nagasaki University · JPYamaguchi University · JPNagasaki University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we investigated severe fever with thrombocytopenia syndrome (SFTS) virus (SFTSV) infection in cats in Nagasaki, Japan. In total, 44 of 133 (33.1%) cats with suspected SFTS were confirmed to be infected with SFTSV. Phylogenetic analyses of SFTSV isolates from cats indicated that the main genotype in Nagasaki was J1 and that unique reassortant strains with J2 (S segment) and unclassified genotypes (M and L segments) were also present. There were no significant differences in virus growth in cell cultures or fatality in SFTSV-infected mice between the SFTSV strains that were isolated from recovered and fatal cat cases. Remarkably, SFTSV RNAs were detected in the swabs from cats, indicating that the body fluids contain SFTSV. To evaluate the risk of SFTSV infection when providing animal care, we further examined the seroprevalence of SFTSV infection in veterinarian staff members; 3 of 71 (4.2%) were seropositive for SFTSV-specific antibodies. Our results provide useful information on the possibility of using cats as sentinel animals and raised concerns of the zoonotic risk of catching SFTSV from animals.

Indexed as

PhlebovirusVeterinariansAnimalsAntibodies, ViralCat DiseasesCatsGenome, ViralHigh-Throughput Nucleotide SequencingImmunoglobulin GJapanPhylogenyRNA, ViralSevere Fever with Thrombocytopenia SyndromeAntibodies, ViralImmunoglobulin GRNA, Viralcatssevere fever with thrombocytopenia syndromeveterinarians

Identifiers

PMID34198717
PMCPMC8232257
OpenAlexW3168041046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.