Evidence map›Paper›PMID 34198701›Full record

ArticleDentistry journal2021

Effects of Different Application Times of Silver Diamine Fluoride on Mineral Precipitation in Demineralized Dentin.

Surapong Srisomboon, Matana Kettratad, Phakkhananan Pakawanit, Catleya Rojviriya, Prathip Phantumvanit, Piyaphong Panpisut

Open access · goldAbstract read
In one paragraph

Article in Dentistry journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. TheBiomaterial investigations in dentistry · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Surapong SrisomboonUnit of Gerodontology, Faculty of Dentistry, Thammasat University, T. Klong 1, A. Klongluang, Pathum Thani 12120, Thailand.
Matana KettratadUnit of Gerodontology, Faculty of Dentistry, Thammasat University, T. Klong 1, A. Klongluang, Pathum Thani 12120, Thailand.ORCID 0000-0002-8789-4080
Phakkhananan PakawanitSynchrotron Light Research Institute (Public Organization), 111 University Avenue, Muang District, Nakhon Ratchasima 30000, Thailand.
Catleya RojviriyaSynchrotron Light Research Institute (Public Organization), 111 University Avenue, Muang District, Nakhon Ratchasima 30000, Thailand.
Prathip PhantumvanitFaculty of Dentistry, Thammasat University, T. Klong 1, A. Klongluang, Pathum Thani 12120, Thailand.
Piyaphong PanpisutFaculty of Dentistry, Thammasat University, T. Klong 1, A. Klongluang, Pathum Thani 12120, Thailand.ORCID 0000-0002-8649-857X
Thammasat University · THSynchrotron Light Research Institute · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silver diamine fluoride (SDF) is a cost-effective method for arresting active dental caries. However, the limited cooperation of patients may lead to an SDF application time that is shorter than the recommended 1-3 min for carious lesions. Therefore, the aim of this study was to assess the effect of different application times of SDF on the degree of mineral precipitation in demineralized dentin. Demineralized dentin specimens from permanent maxillary molars were treated by applying 38% SDF for 30, 60, or 180 s. Water was applied in the control group. The specimens were immersed in simulated body fluid for 2 weeks, and the mineral precipitation in demineralized dentin was then analyzed using FTIR-ATR, SEM-EDX, and synchrotron radiation X-ray tomographic microscopy (SRXTM). The FTIR-ATR results showed a significant increase in mineral precipitation in the 180 s group after 1 week. However, after 2 weeks, the SRXTM images indicated comparable mineral density between the 30, 60, and 180 s groups. The precipitation of silver chloride and calcium phosphate crystals that occluded dentinal tubules was similar in all experimental groups. In conclusion, an application time of either 30, 60, or 180 s promoted a comparable degree of mineral precipitation in demineralized dentin.

Indexed as

application timedemineralizationdental cariesmineral densityremineralizationsilver diamine fluoride

Identifiers

PMID34198701
PMCPMC8232282
OpenAlexW3172911683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.