Evidence map›Paper›PMID 34198671›Full record

ArticleCancers2021

Increased Tumor Growth Rate and Mesenchymal Properties of NSCLC-Patient-Derived Xenograft Models during Serial Transplantation.

José Miguel Pardo-Sánchez, Nuria Mancheño, José Cerón, Carlos Jordá, Emilio Ansotegui, Óscar Juan, Sarai Palanca, Antonio Cremades, Carolina Gandía, Rosa Farràs

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

José Miguel Pardo-SánchezOncogenic Signalling Laboratory, Centro de Investigación Príncipe Felipe, 46012 Valencia, Spain.ORCID 0000-0002-7090-7818
Nuria MancheñoDepartment of Pathology, University and Polytechnic La Fe Hospital, 46026 Valencia, Spain.ORCID 0000-0003-1110-1758
José CerónDepartment of Thoracic Surgery, University and Polytechnic La Fe Hospital, 46026 Valencia, Spain.
Carlos JordáDepartment of Thoracic Surgery, University and Polytechnic La Fe Hospital, 46026 Valencia, Spain.
Emilio AnsoteguiDepartment of Pulmonology, University and Polytechnic La Fe Hospital, 46026 Valencia, Spain.
Óscar JuanDepartment of Medical Oncology, University and Polytechnic La Fe Hospital, 46026 Valencia, Spain.ORCID 0000-0002-7772-9030
Sarai PalancaMolecular Biology Unit, Service of Clinical Analysis, University and Polytechnic La Fe Hospital, 46026 Valencia, Spain.
Antonio CremadesDepartment of Pathology, Hospital Universitario de la Ribera, 46600 Alzira, Spain.
Carolina GandíaOncogenic Signalling Laboratory, Centro de Investigación Príncipe Felipe, 46012 Valencia, Spain.ORCID 0000-0002-4239-4189
Rosa FarràsOncogenic Signalling Laboratory, Centro de Investigación Príncipe Felipe, 46012 Valencia, Spain.ORCID 0000-0003-4931-1494
Hospital Universitari i Politècnic La Fe · ESCentro de Investigacion Principe Felipe · ESHospital de La Ribera · ES

Funding

Instituto de Salud Carlos III PI15-209; PI20-194
6 · The paper itself

Abstract

Non-small-cell lung cancer (NSCLC) is the leading cause of cancer death worldwide. The high mortality is very often a consequence of its late diagnosis when the cancer is already locally advanced or has disseminated. Advances in the study of NSCLC tumors have been achieved by using in vivo models, such as patient-derived xenografts. Apart from drug screening, this approach may also be useful for study of the biology of the tumors. In the present study, surgically resected primary lung cancer samples (

Indexed as

EMTezrinIHCKi67NSCLCPDXproliferationvimentin

Identifiers

PMID34198671
PMCPMC8232339
OpenAlexW3168526803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.