Evidence map›Paper›PMID 34198599›Full record

Observational studyGenes2021

Clinical Evidence for the Importance of the Wild-Type

Danial Roshandel, Jennifer A Thompson, Rachael C Heath Jeffery, Dan Zhang, Tina M Lamey, Terri L McLaren, John N De Roach, Samuel McLenachan, David A Mackey, Fred K Chen

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Single-Cell Transcriptomics onBiomedicines · 2025
    Article
  4. OCT Biomarkers in a Cohort of Patients WithJournal of ophthalmology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Danial RoshandelCentre for Ophthalmology and Visual Science, The University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0002-6716-6406
Jennifer A ThompsonAustralian Inherited Retinal Disease Registry and DNA Bank, Department of Medical Technology and Physics, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia.ORCID 0000-0003-3553-6457
Rachael C Heath JefferyCentre for Ophthalmology and Visual Science, The University of Western Australia, Perth, WA 6009, Australia.
Dan ZhangOcular Tissue Engineering Laboratory, Lions Eye Institute, Nedlands, WA 6009, Australia.
Tina M LameyCentre for Ophthalmology and Visual Science, The University of Western Australia, Perth, WA 6009, Australia.
Terri L McLarenCentre for Ophthalmology and Visual Science, The University of Western Australia, Perth, WA 6009, Australia.
John N De RoachCentre for Ophthalmology and Visual Science, The University of Western Australia, Perth, WA 6009, Australia.
Samuel McLenachanCentre for Ophthalmology and Visual Science, The University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0001-5732-7387
David A MackeyCentre for Ophthalmology and Visual Science, The University of Western Australia, Perth, WA 6009, Australia.
Fred K ChenCentre for Ophthalmology and Visual Science, The University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0003-2809-9930
Lions Eye Institute · AUThe University of Western Australia · AUSir Charles Gairdner Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AllelesPhenotypeAdolescentAdultAgedEye ProteinsFemaleHumansMaleMiddle AgedMutationPedigreeRetinitis PigmentosaEye ProteinsPRPF31 protein, humangenotype-phenotype correlationmicroperimetrymultimodal imagingnatural historyPRPF31retinitis pigmentosaRP11

Identifiers

PMID34198599
PMCPMC8232116
OpenAlexW3169590537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.