ReviewMetabolites2021
Hyperpolarized Metabolic MRI-Acquisition, Reconstruction, and Analysis Methods.
Review in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Physics-embedded CycleGAN for robust metabolite mapping in short-readout deuterium metabolic imaging.Magnetic resonance letters · 2026Article
- Complementary hyperpolarizedNpj imaging · 2026Article
- Technologies and Strategies for Metabolic and Molecular Imaging With Hyperpolarized MRI.Journal of magnetic resonance imaging : JMRI · 2026Review
- Radial multi-echo bSSFP and IDEAL chemical shift separation in k-space for high-speed 3D hyperpolarizedMagnetic resonance in medicine · 2025Article
- Algebraic methods and computational strategies for pseudoinverse-based MR image reconstruction (Pinv-Recon).Scientific reports · 2025Article
- Open-source implementation of X-nuclear sequences using the Pulseq framework.Magnetic resonance in medicine · 2025Article
- Full-Wave Simulation of a Solenoid RF Coil for Small Animal Magnetic Resonance Imaging with a Clinical Scanner.Sensors (Basel, Switzerland) · 2025Article
- Quo Vadis HyperpolarizedZeitschrift fur medizinische Physik · 2025Review
- Hyperpolarized-MRI in Hypertrophic Cardiomyopathy: A Narrative Review.Clinical Medicine Insights. Cardiology · 2025Review
- Enabling SENSE accelerated 2D CSI for hyperpolarized carbon-13 imaging.Scientific reports · 2024Article
- A vendor-neutral EPI sequence for hyperpolarizedMagnetic resonance in medicine · 2024Article
- Hyperpolarized Carbon-13 Magnetic Resonance Imaging: Technical Considerations and Clinical Applications.Korean journal of radiology · 2024Review
- Clinically Translatable HyperpolarizedACS sensors · 2023Article
- Neurons require glucose uptake and glycolysis in vivo.Cell reports · 2023Article
- Detection of increased pyruvate dehydrogenase flux in the human heart during adenosine stress test using hyperpolarized [1-Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022Article
- Hyperpolarized carbon 13 MRI in liver diseases: Recent advances and future opportunities.Liver international : official journal of the International Association for the Study of the Liver · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Hyperpolarized metabolic MRI with 13C-labeled agents has emerged as a powerful technique for in vivo assessments of real-time metabolism that can be used across scales of cells, tissue slices, animal models, and human subjects. Hyperpolarized contrast agents have unique properties compared to conventional MRI scanning and MRI contrast agents that require specialized imaging methods. Hyperpolarized contrast agents have a limited amount of available signal, irreversible decay back to thermal equilibrium, bolus injection and perfusion kinetics, cellular uptake and metabolic conversion kinetics, and frequency shifts between metabolites. This article describes state-of-the-art methods for hyperpolarized metabolic MRI, summarizing data acquisition, reconstruction, and analysis methods in order to guide the design and execution of studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.