Evidence map›Paper›PMID 34198513›Full record

ArticleInternational journal of molecular sciences2021

Activity of Oritavancin and Its Synergy with Other Antibiotics against

Gaoyan Wang, Jia Tang, Jiajia Feng, Wenqi Dong, Xinyu Huo, Hao Lu, Chenchen Wang, Wenjia Lu, Xiangru Wang, Huanchun Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Gaoyan WangState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Jia TangState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Jiajia FengState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Wenqi DongState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Xinyu HuoState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Hao LuState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Chenchen WangState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Wenjia LuState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Xiangru WangState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0003-0191-1378
Huanchun ChenState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Chen TanState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Huazhong Agricultural University · CN

Funding

the National Key R&D Program of China 2017YFD0500303the outstanding youth project of Natural Science Foundation in Hubei Province 2019CFA095
6 · The paper itself

Abstract

backgroundPulmonary disease caused by

methodsWhole-cell growth inhibition assays was performed to screen and identify novel inhibitors. The IC

resultsWe have identified oritavancin as a potential agent against

conclusionsOur in vitro and in vivo assay results indicated that oritavancin may be a viable treatment option against

Indexed as

AnimalsAnti-Bacterial AgentsDisease Models, AnimalDrug SynergismHumansImmunosuppression TherapyIntracellular SpaceLipoglycopeptidesMiceMicrobial Sensitivity TestsMycobacterium abscessusMycobacterium Infections, NontuberculousMycobacterium tuberculosisTHP-1 CellsVancomycinAnti-Bacterial AgentsLipoglycopeptidesoritavancinVancomycinimmunosuppressive mice modelMycobacterium abscessusoritavancinsynergy

Identifiers

PMID34198513
PMCPMC8231898
OpenAlexW3170663225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.