Evidence map›Paper›PMID 34198415›Full record

ArticleMathematical biosciences and engineering : MBE2021

Weakly imposed boundary conditions for shear-rate dependent non-Newtonian fluids: application to cardiovascular flows.

Soonpil Kang, Sharbel Nashar, Elizabeth R Livingston, Arif Masud

Abstract read
In one paragraph

Article in Mathematical biosciences and engineering : MBE, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Modeling of spatiotemporal dynamics of ligand-coated particle flow in targeted drug delivery processes.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Soonpil KangDepartment of Civil and Environmental Engineering, and Department of Biomedical and Translational Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Sharbel NasharDepartment of Civil and Environmental Engineering, and Department of Biomedical and Translational Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Elizabeth R LivingstonDepartment of Civil and Environmental Engineering, and Department of Biomedical and Translational Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Arif MasudDepartment of Civil and Environmental Engineering, and Department of Biomedical and Translational Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

Funding

Stochastic Modeling of Tissue Injury, Edema and Targeted Drug Delivery R01GM135921 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI MASUD, ARIF · 2019 to 2021
$570k
NIGMS NIH HHS R01 GM135921
6 · The paper itself

Abstract

This paper presents a stabilized formulation for the generalized Navier-Stokes equations for weak enforcement of essential boundary conditions. The non-Newtonian behavior of blood is modeled via shear-rate dependent constitutive equations. The boundary terms for weak enforcement of Dirichlet boundary conditions are derived via locally resolving the fine-scale variational equation facilitated by the Variational Multiscale (VMS) framework. The proposed method reproduces the consistency and stabilization terms that are present in the Nitsche type approaches. In addition, for the shear-rate fluids, two more boundary terms appear. One of these terms is the viscosity-derivative term and is a function of the shear-rate, while the other term is a zeroth-order term. These terms play an important role in attaining optimal convergence rates for the velocity and pressure fields in the norms considered. A most significant contribution is the form of the stabilization tensors that are also variationally derived. Employing edge functions the edge stabilization tensor is numerically evaluated, and it adaptively adjusts itself to the magnitude of the boundary residual. The resulting formulation is variationally consistent and the weakly imposed no-slip boundary condition leads to higher accuracy of the spatial gradients for coarse boundary-layer meshes when compared with the traditional strongly imposed boundary conditions. This feature of the present approach will be of significance in imposing interfacial continuity conditions across non-matching discretizations in blood-artery interaction problems. A set of test cases is presented to investigate the mathematical attributes of the method and a patient-specific case is presented to show its clinical relevance.

Indexed as

ViscosityHumansStress, Mechanicalblood flowsinterface stabilizationnon-Newtonian shear-rate dependent fluidsVariational Multiscale methodweakly imposed Dirichlet boundary conditions

Identifiers

PMID34198415
PMCPMC10425273

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.