Evidence map›Paper›PMID 34198413›Full record

ArticleMathematical biosciences and engineering : MBE2021

COVID-19 and underlying health conditions: A modeling investigation.

Chayu Yang, Jin Wang

Open access · goldAbstract read
In one paragraph

Article in Mathematical biosciences and engineering : MBE, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. A two-phase fluid model for epidemic flow.Infectious Disease Modelling · 2023
    Article
  3. An epidemic-economic model for COVID-19.Mathematical biosciences and engineering : MBE · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chayu YangDepartment of Mathematics, University of Florida, Gainesville, FL 32607, USA.
Jin WangDepartment of Mathematics, University of Tennessee at Chattanooga, 615 McCallie Ave., Chattanooga, TN 37403, USA.
University of Florida · US

Funding

Experimentally Guided Modeling and Simulation for Cholera DynamicsR15GM131315 · NIGMS · UNIVERSITY OF TENNESSEE CHATTANOOGA · PI WANG, JIN · 2019 to 2021
$568k
NIGMS NIH HHS R15 GM131315
6 · The paper itself

Abstract

We propose a mathematical model based on a system of differential equations, which incorporates the impact of the chronic health conditions of the host population, to investigate the transmission dynamics of COVID-19. The model divides the total population into two groups, depending on whether they have underlying conditions, and describes the disease transmission both within and between the groups. As an application of this model, we perform a case study for Hamilton County, the fourth-most populous county in the US state of Tennessee and a region with high prevalence of chronic conditions. Our data fitting and simulation results quantify the high risk of COVID-19 for the population group with underlying health conditions. The findings suggest that weakening the disease transmission route between the exposed and susceptible individuals, including the reduction of the between-group contact, would be an effective approach to protect the most vulnerable people in this population group.

Indexed as

COVID-19Computer SimulationHumansModels, TheoreticalPrevalenceSARS-CoV-2chronic conditionsCOVID-19 transmissiondata fitting

Identifiers

PMID34198413
PMCPMC8359646
OpenAlexW3158613976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.