ArticlePloS one2021
Effects of the duration of bridge to lung transplantation with extracorporeal membrane oxygenation.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Characteristics and Progression of Rehabilitation in Patients Undergoing Extracorporeal Membrane Oxygenation: A Retrospective Study.Clinical transplantation · 2026Article
- Association of prolonged ECMO bridging and perioperative factors with dysphagia and survival after lung transplantation.PloS one · 2026Article
- Pediatric Lung Waitlist Score (PLWS): A Score to Predict Waitlist Time for Pediatric Lung Transplant Candidates.Clinical transplantation · 2026Article
- Right ventricular mechanical support as a bridge to lung transplantation: A literature review of current practices.JHLT open · 2025Review
- Improved Results Over Time With Bridge-to-Lung Transplantation: A 10-Year Experience of a Single High-Volume Center.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- ECMO for bridging lung transplantation.European journal of medical research · 2024Review
- Enhancing lung transplantation with ECMO: a comprehensive review of mechanisms, outcomes, and future considerations.The journal of extra-corporeal technology · 2024Review
- Extracorporeal membrane oxygenation as a bridge to lung transplantation: 5-year outcomes and bridge to decision in a large, older cohort.Respiratory research · 2024Article
- Impact of Extracorporeal Membrane Oxygenation Bridging Duration on Lung Transplant Outcomes.The Annals of thoracic surgery · 2024Observational
- Perioperative cardiovascular and cerebrovascular outcomes in recipients of ECMO bridge to lung transplant.JHLT open · 2024Article
- Prognostic factors in lung transplantation after extracorporeal membrane oxygenation bridging therapy: a systematic review and meta-analysis.Journal of thoracic disease · 2024Article
- Severe Lung Dysfunction and Pulmonary Blood Flow during Extracorporeal Membrane Oxygenation.Journal of clinical medicine · 2024Article
- Impact of extracorporeal membrane oxygenation-related complications on in-hospital mortality.PloS one · 2024Article
- Extracorporeal life support as a bridge to lung transplantation: a narrative review.Journal of thoracic disease · 2023Review
- Waitlist Mortality and Extracorporeal Membrane Oxygenation Bridge to Lung Transplant.The Annals of thoracic surgery · 2023Article
- Advances in lung bioengineering: Where we are, where we need to go, and how to get there.Frontiers in transplantation · 2023Review
- Validated Prognostic Scores to Predict Outcomes in ECLS-Bridged Patients to Lung Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Observational
- Lung Transplantation for Acute Respiratory Distress Syndrome.Thoracic surgery clinics · 2022Review
- Extracorporeal membrane oxygenation support before lung transplant: A bridge over troubled water.JTCVS open · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough bridge to lung transplantation (BTT) with extracorporeal membrane oxygenation (ECMO) is increasingly performed, the impact of BTT and its duration on post-transplant outcomes are unclear.
methodsWe retrospectively reviewed medical records of adult patients who underwent lung or heart-lung transplantation in our institution between January 2008 and December 2018. Data were compared in patients who did (n = 41; BTT) and did not (n = 36; non-BTT) require pre-transplant ECMO support. Data were also compared in patients who underwent short-term (<14 days; n = 21; ST-BTT) and long-term (≥14 days; n = 20; LT-BTT) BTTs.
resultsAmong 77 patients included, 51 (66.2%) were male and median age was 53 years. The median bridging time in the BTT group was 13 days (interquartile range [IQR], 7-19 days). Although simplified acute physiologic score II was significantly higher in the BTT group (median, 35; IQR, 31-49 in BTT group vs. median, 12; IQR, 7-19 in non-BTT group; p<0.001), 1-year (73.2% vs. 80.6%; p = 0.361) and 5-year (61.5% vs. 61.5%; p = 0.765) post-transplant survival rates were comparable in both groups. Comparison of ST- and LT-BTT subgroups showed that 1-year (90.5% vs. 55.0%; p = 0.009) and 5-year (73.0% vs. 48.1%; p = 0.030) post-transplant survival rates were significantly higher in ST-BTT group. In age and sex adjusted model, the LT-BTT was an independent risk factor for 1-year post-transplant mortality (hazard ratio, 3.019; 95% confidence interval, 1.119-8.146; p = 0.029), whereas the ST-BTT was not.
conclusionsDespite the severe illness, the BTT group showed favorable post-transplantation outcomes, particularly those bridged for less than 14 days.
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