Evidence map›Paper›PMID 34197303›Full record

ArticleJournal of hospital medicine2021

Outcomes Following Implementation of a Hospital-Wide, Multicomponent Delirium Care Pathway.

Sara C LaHue, Judy Maselli, Stephanie Rogers, Julie Casatta, Jessica Chao, Rhiannon Croci, Ralph Gonzales, Brian Holt, S Andrew Josephson, Sudha Lama and 6 more

Abstract read
In one paragraph

Article in Journal of hospital medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sara C LaHueDepartment of Neurology, School of Medicine, University of California, San Francisco, California.
Judy MaselliDepartment of Medicine, School of Medicine, University of California, San Francisco, California.
Stephanie RogersDepartment of Medicine, School of Medicine, University of California, San Francisco, California.
Julie CasattaDepartment of Neurological Surgery, University of California, San Francisco, California.
Jessica ChaoClinical Innovation Center, University of California, San Francisco, California.
Rhiannon CrociDepartment of Medicine, School of Medicine, University of California, San Francisco, California.
Ralph GonzalesDepartment of Medicine, School of Medicine, University of California, San Francisco, California.
Brian HoltContinuous Improvement Department, University of California, San Francisco, California.
S Andrew JosephsonDepartment of Neurology, School of Medicine, University of California, San Francisco, California.
Sudha LamaDepartment of Medicine, School of Medicine, University of California, San Francisco, California.
Catherine LauDepartment of Medicine, School of Medicine, University of California, San Francisco, California.
Charles McCullochEpidemiology & Biostatistics, University of California, San Francisco, California.
John C NewmanDepartment of Medicine, School of Medicine, University of California, San Francisco, California.
Mark TerrelongeDepartment of Neurology, School of Medicine, University of California, San Francisco, California.
Jan YeagerClinical Innovation Center, University of California, San Francisco, California.
Vanja C DouglasDepartment of Neurology, School of Medicine, University of California, San Francisco, California.

Funding

Geroscience metabolites beta-hydroxybutyrate and NAD+ linking inflammation and neuroenergetic failure in deliriumR01AG068025 · NIA · BUCK INSTITUTE FOR RESEARCH ON AGING · PI NEWMAN, JOHN C · 2020 to 2024
$4.2M
Biological signatures of neurodegeneration and aging associated with delirium in older adults following hip fracture surgeryR03AG074035 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LAHUE, SARA CATHERINE · 2021 to 2022
$323k
NIA NIH HHS R01 AG068025NIA NIH HHS R03 AG074035
6 · The paper itself

Abstract

backgroundDelirium is associated with poor clinical outcomes that could be improved with targeted interventions.

objectiveTo determine whether a multicomponent delirium care pathway implemented across seven specialty nonintensive care units is associated with reduced hospital length of stay (LOS). Secondary objectives were reductions in total direct cost, odds of 30-day hospital readmission, and rates of safety attendant and restraint use.

methodsThis retrospective cohort study included 22,708 hospitalized patients (11,018 preintervention) aged ≥50 years encompassing seven nonintensive care units: neurosciences, medicine, cardiology, general and specialty surgery, hematology-oncology, and transplant. The multicomponent delirium care pathway included a nurse-administered delirium risk assessment at admission, nurse-administered delirium screening scale every shift, and a multicomponent delirium intervention. The primary study outcome was LOS for all units combined and the medicine unit separately. Secondary outcomes included total direct cost, odds of 30-day hospital readmission, and rates of safety attendant and restraint use.

resultsAdjusted mean LOS for all units combined decreased by 2% post intervention (proportional change, 0.98; 95% CI, 0.96-0.99; P = .0087). Medicine unit adjusted LOS decreased by 9% (proportional change, 0.91; 95% CI, 0.83-0.99; P = .028). For all units combined, adjusted odds of 30-day readmission decreased by 14% (odds ratio [OR], 0.86; 95% CI, 0.80-0.93; P = .0002). Medicine unit adjusted cost decreased by 7% (proportional change, 0.93; 95% CI, 0.89-0.96; P = .0002).

conclusionThis multicomponent hospital-wide delirium care pathway intervention is associated with reduced hospital LOS, especially for patients on the medicine unit. Odds of 30-day readmission decreased throughout the entire cohort.

Indexed as

DeliriumHospitalsHumansRetrospective Studies

Identifiers

PMID34197303
PMCPMC9621338

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.