Evidence map›Paper›PMID 34196951›Full record

ArticlePharmacological reports : PR2021

Characterization of dopamine D

Iker Egusquiza, Eva Munarriz-Cuezva, Rafael Segarra, Javier González-Maeso, Luis F Callado, J Javier Meana, Rebeca Diez-Alarcia

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmacological reports : PR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Iker Egusquiza *Department of Pharmacology, University of the Basque Country UPV/EHU, 48940, Leioa, Bizkaia, Spain.
Eva Munarriz-Cuezva *Department of Pharmacology, University of the Basque Country UPV/EHU, 48940, Leioa, Bizkaia, Spain.ORCID http://orcid.org/0000-0003-1943-3642
Rafael SegarraCentro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Leioa, Spain.ORCID http://orcid.org/0000-0002-2033-8151
Javier González-MaesoDepartment of Physiology and Biophysics, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Luis F CalladoDepartment of Pharmacology, University of the Basque Country UPV/EHU, 48940, Leioa, Bizkaia, Spain.ORCID http://orcid.org/0000-0001-9941-012X
J Javier MeanaDepartment of Pharmacology, University of the Basque Country UPV/EHU, 48940, Leioa, Bizkaia, Spain.ORCID http://orcid.org/0000-0002-7913-6714
Rebeca Diez-AlarciaDepartment of Pharmacology, University of the Basque Country UPV/EHU, 48940, Leioa, Bizkaia, Spain. r.diezalarcia@ehu.eus.ORCID http://orcid.org/0000-0002-0806-9825
University of the Basque Country · ESVirginia Commonwealth University · US

Funding

Preclinical role of HDAC2 in mGlu2-dependent schizophrenia treatmentR01MH111940 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI GONZÁLEZ-MAESO, JAVIER · 2017 to 2021
$1.5M
Eusko Jaurlaritza (ES) IT1211/19Eusko Jaurlaritza (ES) KK-2019/00049Foundation for the National Institutes of Health NIH-R01MH111940Foundation for the National Institutes of Health R01MH084894NIMH NIH HHS R01 MH111940Spanish State Research Agency and EDR Funds PID2019-106404RB-100Spanish State Research Agency and EDR Funds SAF-2017-88126-R
6 · The paper itself

Abstract

backgroundAlterations of dopamine D

methodsG-protein receptor coupling was assessed in control caudate nucleus and frontal cortex by [

resultsIn caudate, [

conclusionsFeasibility of functional evaluation of dopamine receptors in postmortem human brain by conventional [

Indexed as

AdultAntipsychotic AgentsDopamineDopamine AgonistsFemaleFrontal LobeGTP-Binding ProteinsGuanosine 5'-O-(3-Thiotriphosphate)HumansMaleMiddle AgedNeuronsReceptors, Dopamine D1Receptors, Dopamine D2SchizophreniaSignal TransductionAntipsychotic AgentsDopamineDopamine AgonistsGTP-Binding ProteinsGuanosine 5'-O-(3-Thiotriphosphate)Receptors, Dopamine D1Receptors, Dopamine D2[35S]GTPγSD2 receptorsDopamineG proteinHuman brainSchizophrenia

Identifiers

PMID34196951
PMCPMC8413194
OpenAlexW3175465000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.